Use of histology is the key when evaluation of bone and soft tissue integration of any implanted metallic prosthesis is required. This relies on the ability to prepare very thin sections by grinding down resin embedded samples. Manual grinding has historically been used with variable success, and thus, a number of commercial microgrinders have been previously marketed, however, at a significant cost. The following describes a practical method to 3D print and build a microgrinder construct retrofitted to a metallurgic wheel grinder/polisher previously available. The design files are also supplied, which allow one to implement customized modifications for virtually all types of wheel grinders/polishers circumventing the need to procure highly costly appliances. Recommendations are included on how to safely and reproducibly prepare microscopic sections using the described construct.
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http://dx.doi.org/10.1080/01478885.2023.2205617 | DOI Listing |
J Bone Joint Surg Am
October 2024
Musculoskeletal Tumor Center, Department of Orthopedics, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, People's Republic of China.
Background: Pelvic reconstruction after type I + II (or type I + II + III) internal hemipelvectomy with extensive ilium removal is a great challenge. In an attempt to anatomically reconstruct the hip rotation center (HRC) and achieve a low mechanical failure rate, a custom-made, 3D-printed prosthesis with a porous articular interface was developed. The aim of this study was to investigate the clinical outcomes of patients treated with this prosthesis.
View Article and Find Full Text PDFVet Sci
December 2024
Department of Surgery, College of Veterinary Medicine, Jeonbuk National University, Iksan-si 56896, Republic of Korea.
Cryotherapy is widely used in veterinary medicine to manage pain and swelling, yet optimal methods for specific tissue depths remain unclear. Cryotherapy modalities, including cold packs (CPs), cold compression (CC), and hyperbaric gaseous cryotherapy (HGC), were applied to nine beagle dogs under general anaesthesia. A custom 3D-printed guide facilitated consistent and accurate measurements of tissue temperatures at depths of 1 and 3 cm.
View Article and Find Full Text PDFJ Funct Biomater
December 2024
Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong, China.
Surgery is considered the gold standard for treating melanoma, but the high recurrence rate after surgery still remains as a major challenge. Therefore, using doxorubicin (DOX) as a model drug, this study investigated the 3D printing of anticancer drug-loaded hydrogel blend scaffolds for inhibiting post-operation melanoma recurrence and for promoting tissue regeneration. Three-dimensional printing could successfully produce methacrylate-modified chitosan (CSMA) and methylcellulose (MC) hydrogel blend scaffolds.
View Article and Find Full Text PDFBiomimetics (Basel)
December 2024
Department of Mechanical Engineering and Aeronautics, University of Patras, 26504 Patras, Greece.
3D-printed biomedical polylactic acid (PLA) scaffolds were developed, and their biodegradation, as well as their thermomechanical behavior, were studied in a relevant in vitro environment. The scaffold's biodegradability profile has been monitored after immersion in a cell culture medium that contains components of blood and body fluids. Two types of biodegradation experiments were performed-a standard static one and an adapted stirring one, mimicking the body fluids' flow, respectively-to achieve a comparative investigation.
View Article and Find Full Text PDFCureus
November 2024
General Dentistry and Comprehensive Care, NYU College of Dentistry, New York University, New York, USA.
Objectives To assess the influence of cigarette smoke (CS) on the color and surface roughness of 3D printed, milled, and traditionally fabricated provisional crown and bridge (PC&B) materials. Materials and methods 112 disc-shaped samples were made employing four techniques and materials (28 per group) to fabricate PC&B prostheses. Specimens were fabricated using standard protocols, such as 3D printing, milling, conventional bis-acrylic resin, and traditional autopolymerizing polymethyl methacrylate (PMMA) resin.
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