Purpose: Patient positioning and immobilization devices are commonly employed in radiation therapy. Unfortunately, cases can arise where the devices need to be reconstructed or improved. This work describes clinical processes to use a planning CT, to design and 3D print immobilization devices for reproducible patient positioning within a clinically feasible time frame when traditional methods can no longer be used or are insufficient.
Materials/methods: Three clinical cases required rapid 3D printing of an immobilization device mid-treatment due to the following: (1) a lost headrest cushion, (2) needed improvement in lumbar spine positioning, and (3) a partially deflated vacuum immobilization mattress.
Results: In the three cases, the 3D printed immobilization devices were clinically implemented successfully; two of the devices were fully designed and printed in 1 day. The 3D printed immobilization devices achieved a positioning accuracy sufficient to avoid the necessity to repeat the simulation and planning process.
Conclusion: If traditional immobilization devices fail or are misplaced, it is feasible to have a 3D printed replacement within the time span of 1 day. The design and fabrication methods, as well as the experiences gained, are described in detail to assist clinicians to implement 3D printing for similar situations.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402670 | PMC |
| http://dx.doi.org/10.1002/acm2.14008 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Spatial accuracy of dose delivery significantly impacts the planning target volume margin in linear accelerator-based intracranial stereotactic radiosurgery.
Sci Rep
January 2025
Radiation Safety and Quality Assurance division, National Cancer Center Hospital East, Chiba, 277-8577, Japan.
The impact of three-dimensional (3D) dose delivery accuracy of C-arm linacs on the planning target volume (PTV) margin was evaluated for non-coplanar intracranial stereotactic radiosurgery (SRS). A multi-institutional 3D starshot test using beams from seven directions was conducted at 22 clinics using Varian and Elekta linacs with X-ray CT-based polymer gel dosimeters. Variability in dose delivery accuracy was observed, with the distance between the imaging isocenter and each beam exceeding 1 mm at one institution for Varian and nine institutions for Elekta.
View Article and Find Full Text PDFCarbon quantum dot-anchored polyaniline on electrospun carbon nanofibers as freestanding electrodes for symmetric solid-state supercapacitors.
Dalton Trans
January 2025
Key Laboratory for Photonic and Electronic Bandgap Materials, Ministry of Education, School of Physics and Electronic Engineering, Harbin Normal University, Harbin 150025, People's Republic of China.
A binder-free and freestanding electrode was designed by uniformly immobilizing carbon quantum dot (CQD)-anchored polyaniline (PANI) heterostructures onto electrospun carbon nanofibers (CNFs) a facile hierarchical assembly process. The fabricated freestanding CNF/PANI/CQD electrode exhibits a unique three-dimensional (3D) network nanostructure, which accelerates ion migration between the interior and surface of the electrode, thereby enhancing its charging and discharging performance. Moreover, the functional groups on the surface of CQDs could anchor PANI through possible chemical bonding, which not only improves the stability of the PANI/CQD heterojunction but also creates an additional conductive channel for the PANI polymer.
View Article and Find Full Text PDFElectrochemical aptasensor for the selective detection of vancomycin based on nanostructured "in-lab" printed electrodes.
Mikrochim Acta
January 2025
Department of Analytical Chemistry, Faculty of Pharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 4 Pasteur Street, 400349, Cluj-Napoca, Romania.
A label-free, flexible, and disposable aptasensor was designed for the rapid on-site detection of vancomycin (VAN) levels. The electrochemical sensor was based on lab-printed carbon electrodes (C-PE) enriched with cauliflower-shaped gold nanostructures (AuNSs), on which VAN-specific aptamers were immobilized as biorecognition elements and short-chain thiols as blocking agents. The AuNSs, characterized by scanning electron microscopy (SEM) and atomic force microscopy (AFM), enhanced the electrochemical properties of the platform and the aptamer immobilization active sites.
View Article and Find Full Text PDFDevelopment of detection system for lead ions in mixture solutions using UV-Vis measurements with peptide immobilized microbeads.
Sci Rep
January 2025
Faculty of Frontiers of Innovative Research in Science and Technology (FIRST), Konan University, Chuo-ku, Kobe, 650-0047, Hyogo, Japan.
Environmental pollution caused by heavy metals are problems worldwide. In particular, pollution and poisoning by lead ions (Pb) continue to be common and serious problems. Hence, there is a need for a widely usable method to easily detect Pb from solutions containing organic materials from environmental water such as seas, ponds, etc.
View Article and Find Full Text PDFAtmospheric air plasma pre-activation and customizable covalent functionalization of PVDF-membranes of microtiter filter plates.
Sci Rep
January 2025
Department of Pharmaceutical Chemistry, Semmelweis University, Hőgyes Endre U. 9, 1092, Budapest, Hungary.
Microtiter-plate-based systems are unified platforms of high-throughput experimentation (HTE). These polymeric devices are used worldwide on a daily basis-mainly in the pharmaceutical industry-for parallel syntheses, reaction optimization, various preclinical studies and high-throughput screening methods. Accordingly, laboratory automation today aims to handle these commercially available multiwell plates, making developments focused on their modifications a priority area of modern applied research.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!