Tuberculosis (TB) and mental illnesses frequently coexist and are both extremely common worldwide. Through the National Program for Elimination of Tuberculosis (NTEP), anti-tuberculosis therapy (ATT) medications are used to treat tuberculosis in India. We want to report a case 45-year-old patient from the state of Andhra Pradesh, India with comorbid delusional disorder leading to daily ATT drug consumption for the past 20 years. This unusual presentation demonstrates that abuse of a Schedule "H" substance like ATT is also conceivable. To stop "Off-label" purchases, strict measures must be taken. Before beginning ATT, evaluating the patient's mental health may be a wise move.
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http://dx.doi.org/10.7759/cureus.36893 | DOI Listing |
Schizophr Bull
January 2025
Clinical, Educational and Health Psychology, University College London, London, WC1E 6BT, UK.
Background And Hypothesis: Delusions are classified into themes but the range of themes reported in the literature has never been examined and the extent to which they differ in prevalence, or relate to clinical characteristics or cultural variation, remains poorly understood.
Study Design: We identified studies reporting delusional theme prevalence in adults with psychosis and completed two multivariate, multilevel, random-effects meta-analyses: one including data from structured assessment scales only and another also including data from ad hoc and clinical assessments to include themes from a wider range of countries and contexts. Sensitivity and meta-regression analyses examined the association with clinical and methodological variables.
We describe a 23-year-old woman with erotomania as a symptom of complicated grief. The delusional disorder emerged after a breakup with her partner, during a period of complicated grief following the unexpected loss of her twin brother. The delusion potentially functioned as a protection against a recurrent depressive disorder.
View Article and Find Full Text PDFCureus
December 2024
Department of Medicine, Tower Health Medical Group, Reading, USA.
Objective: The recent development of xylazine adulteration of the illicit opiate supply has been associated with necrotic extremity wounds of unclear pathogenesis. This study sought to understand the prevalence and characteristics of delusional infestation (DI) among patients with opiate use disorders who also carried a diagnosis of cellulitis.
Methods: A retrospective cross-sectional study was performed in one health system to identify patients with opiate use disorder and cellulitis over the past three years who also described symptoms of DI.
BMJ Case Rep
January 2025
Rheumatology, Epsom and Saint Helier Hospital NHS Trust, Carshalton, UK.
A young lady was brought to the hospital by the police after they found her wandering in the streets far away from her home behaving oddly. At admission, she was confused and had various delusional thoughts accompanied by visual and auditory hallucinations. After she was identified and her old medical notes were retrieved, it was found that she had a diagnosis of systemic lupus erythematosus (SLE) previously for which she declined any treatment.
View Article and Find Full Text PDFBrain
January 2025
Department of Psychiatry (UPK), University of Basel, 4001 Basel, Switzerland.
Perception integrates external sensory signals with internal predictions that reflect prior knowledge about the world. Previous research suggests that this integration is governed by slow alternations between an external mode, driven by sensory signals, and an internal mode, shaped by prior knowledge. Using a double-blind, placebo-controlled, cross-over experiment in healthy human participants, we investigated the effects of the N-Methyl-D-aspartate receptor (NMDAR) antagonist S-ketamine on the balance between external and internal modes.
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