The metaverse is a unified, persistent, and shared multi-user virtual environment with a fully immersive, hyper-temporal, and diverse interconnected network. When combined with healthcare, it can effectively improve medical services and has great potential for development in realizing medical training, enhanced teaching, and remote surgical treatment. The metaverse provides immersive services for users through massive and multimodal data, and its data scale and data growth rate are bound to show exponential growth. Blockchain-based distributed storage is a fundamental way to keep the metaverse running continuously; however, many blockchains, such as Ethereum and Filecoin, suffer from low transaction throughput and high latency, which seriously affect the efficiency of distributed storage services and make it difficult to apply them to the metaverse environment. To this end, this paper first proposes a network architecture for distributed storage systems based on proof of retrievability to address the problem of centralized decision making and single point of access in centralized storage. The secure data storage of the metaverse health system is ensured. Secondly, we designed two data transmission protocols through vector commitment and encoding functions to achieve the transfer of time cost from the critical path to storage nodes and improve the efficiency of data verification between nodes as well as the scalability of the metaverse health system. Finally, this paper also conducts security analysis and performance analysis of the proposed scheme, and the results show that our scheme is secure and efficient.
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http://dx.doi.org/10.1109/JBHI.2023.3272021 | DOI Listing |
AAPS J
January 2025
Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.
Freeze drying is one of the common methods to extend the long-term stability of biologicals. Biological products in solid form have the advantages of convenient transportation and stable long-term storage. However, long reconstitution time and extensive visible bubbles are frequently generated during the reconstitution process for many freeze-dried protein formulations, which can potentially affect the management efficiency of staff, patient compliance, and product quality.
View Article and Find Full Text PDFNat Commun
January 2025
State Key Lab of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing, China.
Polymer dielectric materials are widely used in electrical and electronic systems, and there have been increasing demands on their dielectric properties at high temperatures. Incorporating inorganic nanoparticles into polymers is an effective approach to improving their dielectric properties. However, the agglomeration of inorganic nanoparticles and the destabilization of the organic-inorganic interface at high temperatures have limited the development of nanocomposites toward large-scale industrial production.
View Article and Find Full Text PDFProg Mol Biol Transl Sci
January 2025
School of Health Sciences & Technology, UPES, Dehradun, Uttarakhand, India. Electronic address:
A new era in genomic medicine has been brought by the development of CRISPR-Cas technology, which presents hitherto unheard-of possibilities for the treatment of metabolic illnesses. The treatment approaches used in CRISPR/Cas9-mediated gene therapy, emphasize distribution techniques such as viral vectors and their use in preclinical models of metabolic diseases like hypercholesterolemia, glycogen storage diseases, and phenylketonuria. The relevance of high-throughput CRISPR screens for target identification in discovering new genes and pathways associated with metabolic dysfunctions is an important aspect of the discovery of new approaches.
View Article and Find Full Text PDFSci Total Environ
January 2025
Department of Biotechnology, University of Verona, strada Le Grazie 15, 37134 Verona, Italy. Electronic address:
Understanding the accumulation and stability of soil organic matter (SOM) pools as a function of time (i.e., soil age) and climate (i.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
January 2025
Northeast Normal University, Department of Chemistry, Renmin Street 5268, 130024, Changchun, CHINA.
Aqueous zinc-iodine batteries (AZIBs) are gaining attention as next-generation energy storage systems due to their high theoretical capacity, enhanced safety, and cost-effectiveness. However, their practical application is hindered by challenges such as slow reaction kinetics and the persistent polyiodide shuttle effect. To address these limitations, we developed a novel class of covalent organic frameworks (COFs) featuring electron-rich nitrogen sites with varied density and distribution (N1-N4) along the pore walls.
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