https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=37124592&retmode=xml&tool=Litmetric&email=readroberts32@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09 3712459220240502
0970-91343932023MayIndian journal of thoracic and cardiovascular surgeryIndian J Thorac Cardiovasc SurgLeft ventricular mass regression after aortic valve replacement with the TTK Chitra™ monoleaflet tilting disc valve.238243238-24310.1007/s12055-022-01468-2To study the extent of left ventricular (LV) mass regression in aortic stenosis after aortic valve replacement with the TTK Chitra™ tilting disc valve.This study included patients with severe isolated aortic stenosis (AS), admitted in our department. They had aortic valve replacement (AVR) with the TTK Chitra™ tilting disc valve, between January 2008 and December 2010. Data were collected from consecutive forty-eight patients. LV mass and diametric and functional parameters were recorded preoperatively and compared with echocardiography after 3 months, 6 months, then yearly, up to 3 years.70.8% of the patients were males and 29.2% were females. The mean duration of illness was 37.92 ± 25.87 months. The mean LV ejection fraction increased 3 months after surgery (61.56 ± 10.10% to 69.31 ± 9.34%) with a sustained increase for the next 3 years. The mean LV end-diastolic diameter decreased (50.16 ± 6.05 mm to 45.69 ± 5.93 mm) after 3 months of surgery, with a sustained decrease for the next 3 years. The mean LV end-systolic diameter decreased (32.84 ± 6.96 mm to 29.41 ± 5.86 mm) after 3 months of surgery and then showed a sustained decrease for the next 3 years. The LV mass assessed with echocardiography regressed from 324.65 ± 97.77 g before surgery to 252.64 ± 71.12 g after 3 months and then showed a sustained decrease over the next 3 years.Significant LV mass regression occurred after AVR with the TTK Chitra™ valve. The maximum reversal was found to be within the first 3 months after surgery with sustained beneficial improvement for the next 3 years.© Indian Association of Cardiovascular-Thoracic Surgeons 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.VeerapudranSivaprasadS0000-0003-2359-6292Department of Cardiovascular and Thoracic Surgery, Sree ChitraTirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695011 India.grid.416257.30000 0001 0682 4092Trivandrum, India.DamodaranDeepthiDDepartment of Physiology, Medical College Thiruvananthapuram, Thiruvananthapuram, Kerala India.grid.413226.00000 0004 1799 9930PillaiVivek VelayudhanVVDepartment of Cardiovascular and Thoracic Surgery, Sree ChitraTirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695011 India.grid.416257.30000 0001 0682 4092NatarajanGeethaGDepartment of Physiology, Medical College Thiruvananthapuram, Thiruvananthapuram, Kerala India.grid.413226.00000 0004 1799 9930PillaiPremalathatha Thachakuzhiyil KrishnaPTKDepartment of Physiology, Medical College Thiruvananthapuram, Thiruvananthapuram, Kerala India.grid.413226.00000 0004 1799 9930KarunakaranJayakumarJDepartment of Cardiovascular and Thoracic Surgery, Sree ChitraTirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695011 India.grid.416257.30000 0001 0682 4092engJournal Article20230204
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