The purpose of this investigation was to determine the effect of different relative pressures of blood flow restriction (BFR) on muscle oxygen saturation (SmO) while walking at 3.0 mph (4.83 kph). Fifteen physically active healthy adults performed seven 5-minute stages of walking at 3.0 mph with a blood flow restriction cuff applied to the proximal portion of the left or right leg while bilateral SmO changes were measured using near infra-red spectroscopy (NIRS) on the medial head of the gastrocnemius (GM) and vastus lateralis (VL) muscles. Other measurements including heart rate (HR), blood pressure (BP), rating of perceived exertion (RPE), and ground contact time balance (GCTB) were also collected. SmO measurements were analyzed using two-way repeated measures (RM) ANOVA while other measurements were analyzed using one-way RM ANOVA. We observed a significant main effect of LOP% (limb occlusion pressure) on the difference in total area of desaturation that occurred during each occlusion stage (ADS), < 0.0001 η = .336, early ΔSmO, < 0.0001 in both the GAS η = .132 and VL η = .335. The results suggest that there are significant differences in SmO desaturation between 40%, 80%, and 100% LOP. Our findings suggest that incremental increases in LOP will bring about greater SmO desaturation during walking and may therefore induce a larger adaptive response on the muscles. However, increased LOP% may intensify perception of effort.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128124PMC
http://dx.doi.org/10.70252/KCIF2483DOI Listing

Publication Analysis

Top Keywords

blood flow
12
flow restriction
12
muscle oxygen
8
oxygen saturation
8
walking mph
8
measurements analyzed
8
smo desaturation
8
smo
5
effects percentages
4
blood
4

Similar Publications

Background: Primary percutaneous coronary intervention (PPCI) and fibrinolytic or thrombolytic therapy are common treatments for ST-elevation myocardial infarction (STEMI). Primary percutaneous coronary intervention is more effective than thrombolytic therapy, but fibrinolytic therapy is still a preferable option for patients with limited access to healthcare. Alteplase is a tissue plasminogen activator (tPA) used to treat acute myocardial infarction, acute ischemic stroke, and pulmonary embolism.

View Article and Find Full Text PDF

Swine are increasingly utilized in cardiovascular research due to their anatomical and physiological similarities to humans, particularly for studying diastolic dysfunction. While MRI offers excellent structural imaging, echocardiography provides superior real-time assessment of diastolic parameters. To address the lack of standardized methods and reduce variability across studies, we present a comprehensive guide for performing echocardiography in Yorkshire pigs, detailing anatomical considerations, equipment requirements, and technical approaches.

View Article and Find Full Text PDF

Objectives: We evaluated the performance of a novel flow cell morphology analyzer AUTION EYE AI-4510 for counting particles in urine.

Methods: Analytical performance was assessed according to the EFLM European Urinalysis Guideline 2023. Trueness was compared by analyzing 1.

View Article and Find Full Text PDF

Hyperpolarized Xe MRI/MRS enables quantitative mapping of function in lung airspaces, membrane tissue, and red blood cells (RBCs) within the pulmonary capillaries. The RBC signal also exhibits cardiogenic oscillations that are reduced in pre-capillary pulmonary hypertension (PH). This effect is obscured in patients with concomitant defects in transfer from airspaces to RBCs, which increase RBC oscillation amplitudes.

View Article and Find Full Text PDF

Wave-CAIPI Multiparameter MR Imaging in Neurology.

NMR Biomed

March 2025

Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.

In clinical practice, particularly in neurology assessments, imaging multiparametric MR images with a single-sequence scan is often limited by either insufficient imaging contrast or the constraints of accelerated imaging techniques. A novel single scan 3D imaging method, incorporating Wave-CAIPI and MULTIPLEX technologies and named WAMP, has been developed for rapid and comprehensive parametric imaging in clinical diagnostic applications. Featuring a hybrid design that includes wave encoding, the CAIPIRINHA sampling pattern, dual time of repetition (TR), dual flip angle (FA), multiecho, and optional flow modulation, the WAMP method captures information on RF B1t fields, proton density (PD), T1, susceptibility, and blood flow.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!