Introduction: The palmaris longus muscle displays a great variation in terms of incidence and shape. This study has documented the incidence ratio of this muscle among the students at Bolu Abant İzzet Baysal University, Faculty of Medicine, and has revealed the effects of its presence on wrist proprioception and grip strength.
Methods: A total of 101 students between the ages of 18 and 25 were included in the study. Age, height, weight, body mass index (BMI), and dominant upper extremity of the individuals were recorded. After the presence of palmaris longus tendon (PLT) was determined by using the Schaeffer's test, wrist proprioception was evaluated by using a digital inclinometer, and grip strength was evaluated by using a hand dynamometer.
Results: PLT absence rates were evaluated separately as right and left, and it was found as 16.8% and 17.8%. No correlation was found between the dominant upper extremity and BMI and the presence of PLT. The presence or absence of PLT has no effect on grip strength and wrist proprioception. Conclusion: PLT is used in many clinical areas, such as reconstructive and cosmetic surgery, graft applications, tendon repairs, ptosis correction operations, and ligament stabilization. We think there will be no significant loss in the sense of proprioception and grip strength in the absence of PLT.
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http://dx.doi.org/10.7759/cureus.36779 | DOI Listing |
Eur J Nutr
January 2025
School of Physical Education and Sport Science, National and Kapodistrian University of Athens, 17237, Athens, Greece.
Purpose: Protein supplementation has been proposed as an effective dietary strategy for maintaining or increasing skeletal muscle mass and improving physical performance in middle-aged and older adults. Diabetes mellitus exacerbates muscle mass loss, leading to many older adults with type 2 diabetes mellitus (T2DM) experiencing sarcopenia, and vice versa. Our objective was to assess the impact of increased dietary protein intake on muscle mass, strength, physical performance, and the progression of T2DM in middle-aged and older adults diagnosed with this condition.
View Article and Find Full Text PDFCalcif Tissue Int
January 2025
MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton General Hospital, Southampton, UK.
Previous studies suggest social support is associated with musculoskeletal health in later life. We explored this relationship further in community-dwelling older adults, by considering associations between different aspects of social support and musculoskeletal health in community-dwelling adults. Participants from the Hertfordshire Cohort Study reported level of confiding/emotional, practical, and negative support using the Close Persons Questionnaire.
View Article and Find Full Text PDFCalcif Tissue Int
January 2025
School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, People's Republic of China.
This study aims to identify novel loci associated with sarcopenia-related traits in UK Biobank (UKB) through multi-trait genome-wide analysis. To identify novel loci associated with sarcopenia, we integrated the genome-wide association studies (GWAS) of usual walking pace (UWP) and hand grip strength (HGS) to conduct a joint association study known as multi-trait analysis of GWAS (MTAG). We performed a transcriptome-wide association study (TWAS) to analyze the results of MTAG in relation to mRNA expression data for genes identified in skeletal muscle.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Background: Emerging evidence support the notion that loss of splicing repression by TDP-43, an RNA binding protein that was first implicated in ALS-FTD, underlies their pathogenesis. Previously, we showed that delivery of an AAV9 vector at early postnatal day expressing a fusion protein, termed CTR comprised of the N-terminal region of TDP-43 and an unrelated splicing repressor termed RAVER1 complemented the loss of TDP-43 in mice lacking TDP-43 in spinal motor neurons (ChAT-IRES-Cre;tardbp mice). To translate this potential therapeutic strategy to the clinic, it will be important to demonstrate benefit of such AAV delivery of CTR to motor neurons in adult mice.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN, USA.
Background: Tau aggregation is the major cause of several neurodegenerative tauopathies. Tau interaction with other proteins affects the formation of tau aggregates with seeding activity but less is known about its effects on tau-seed properties. Our previous study revealed that Bassoon (BSN), a presynaptic protein, interacts with tau-seed, exacerbating its toxicity in vivo.
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