The aims of the present study were to investigate (1) whether the COVID-19 pandemic and the restrictive measures to control its spread were associated with changes in happiness before and after the pandemic and (2) whether household size, living with a partner/spouse, living with at least one son/daughter, financial support, income loss, and job loss following the pandemic were associated with happiness after controlling for previous levels of happiness. We use data from the Italian Survey on Household Income and Wealth (SHIW). Specifically, we used longitudinal data from 2283 respondents who participated in the SHIW 2016 and SHIW 2020. Results revealed a small but significant increase in happiness from 2016 to 2021. In addition, living with a partner/spouse predicted higher happiness with a medium effect size, and total income loss predicted lower happiness with a small to medium effect size. Household size, living with at least one son/daughter, financial support, partial income loss, and job loss following the pandemic were unrelated to happiness.
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http://dx.doi.org/10.1016/j.ijdrr.2023.103711 | DOI Listing |
BMC Health Serv Res
January 2025
HIV and Other Infectious Diseases Research Unit (HIDRU), South African Medical Research Council: CAPRISA-MRC HIV-TB Pathogenesis and Treatment Research Unit, Free State, South Africa.
Background: Despite advances in drug-resistant tuberculosis (DR-TB) diagnosis, treatment, and service delivery, individuals with DR-TB often face significant socioeconomic and psychosocial challenges due to limited resources. These challenges can hinder retention in care, undermining the progress made in DR-TB management. As a consequence, advances in DR-TB diagnostics and treatment have not resulted in DR-TB programs meeting the 75% treatment success targets set by the World Health Organization (WHO).
View Article and Find Full Text PDFBMJ Paediatr Open
January 2025
Department of Population Health, New York University Grossman School of Medicine, New York, New York, USA
Greenhouse gas (GHG) emissions are creating unprecedented climate-driven extreme weather, with levels of heat and humidity surpassing human physiological tolerance for heat stress. These conditions create a risk of mass casualties, with some populations particularly vulnerable due to physiological, behavioural and socioeconomic conditions (eg, lack of adequate shelter, limited healthcare infrastructure, sparse air conditioning access and electrical grid vulnerabilities). Children, especially young children, are uniquely vulnerable to extreme heat-related morbidity and mortality due to factors including low body mass, high metabolism, suboptimal thermoregulatory mechanisms and behavioural vulnerabilities.
View Article and Find Full Text PDFA 1.5 to 3 Mb microdeletion of chromosome 22q11.2 with loss of multiple genes including histone cell cycle regulator (HIRA) causes 22q11.
View Article and Find Full Text PDFJ Clin Epidemiol
January 2025
Univ Rennes, CHU Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Centre d'investigation clinique de Rennes (CIC1414), Rennes, France; Institut Universitaire de France (IUF), Paris, France.
Guided by the FAIR principles (Findable, Accessible, Interoperable, Reusable), responsible data sharing requires well-organized, high-quality datasets. However, researchers often struggle with implementing Data Management and Sharing Plans (DMSPs) due to lack of knowledge on how to do this, time constraints, legal, technical and financial challenges, particularly concerning data ownership and privacy. While patients support data sharing, researchers and funders may hesitate, fearing the loss of intellectual property or competitive advantage.
View Article and Find Full Text PDFBiomedica
December 2024
Grupo de Inmunodeficiencias Primarias, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
Introduction: Common variable immunodeficiency is a diagnosis of exclusion in immunodeficient patients with increased susceptibility to infections, hypogammaglobulinemia, deficient response to vaccination, or low percentages of switched memory B cells. In low- and middle-income countries, the elucidation and study of molecular defects in these patients may take decades.
Objective: To elucidate the genetic defect conferring impaired immunity in a patient diagnosed with common variable immunodeficiency.
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