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Estimating the Benefits of Oral Cancer Screening: Challenges and Opportunities.
Cancers (Basel)
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Melbourne Dental School, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Carlton, VIC 3010, Australia.
Screening is widely believed to facilitate early detection and improve health outcomes; however, recent evidence questions its overall benefits, highlighting the need for a critical assessment of cancer screening programs. The simplicity of clinical oral examination and the easy accessibility of the oral cavity make oral cancer a suitable candidate for opportunistic screening. Despite this uniqueness, studies that solidly assess the efficacy and cost-effectiveness of oral cancer screening are scanty, and the only large randomized trial undertaken so far shows limited evidence of mortality reduction through population screening.
View Article and Find Full Text PDFThe use-the-best heuristic facilitates deception detection.
Nat Hum Behav
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Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, the Netherlands.
Decades of research have shown that people are poor at detecting deception. Understandably, people struggle with integrating the many putative cues to deception into an accurate veracity judgement. Heuristics simplify difficult decisions by ignoring most of the information and relying instead only on the most diagnostic cues.
View Article and Find Full Text PDFThe deceptive simplicity of mendelian genetics.
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Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland.
Mendel, a genius experimentalist, meticulously uncovered the genetic basis of heredity in work that transformed the science of biology. But does the alluring simplicity of Mendel's laws sometimes obscure the true complexity of genetics?
View Article and Find Full Text PDFDisentangling compartment functions in sessile marine invertebrates.
Trends Ecol Evol
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University of Technology Sydney, Climate Change Cluster, Ultimo, NSW 2007, Australia; Marine Biology Section, Department of Biology, University of Copenhagen, Strandpromenaden 5, DK 3000 Helsingør, Denmark. Electronic address:
Sessile invertebrates are frequently sampled and processed whole for downstream analyses. However, their apparent structural simplicity is deceptive as these organisms often harbour discrete compartments. These compartments have physicochemical conditions that differ markedly from neighbouring tissues, and that have likely evolved to support specific functions.
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