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Cyclophilin A is a ligand for RAGE in thrombo-inflammation.
Cardiovasc Res
March 2024
Department of Cardiology and Angiology, Universitätsklinikum Tübingen, Eberhard Karls University Tübingen, Otfried-Müller-Str. 10, 72076 Tübingen, Germany.
Aims: Cyclophilin A (CyPA) induces leucocyte recruitment and platelet activation upon release into the extracellular space. Extracellular CyPA therefore plays a critical role in immuno-inflammatory responses in tissue injury and thrombosis upon platelet activation. To date, CD147 (EMMPRIN) has been described as the primary receptor mediating extracellular effects of CyPA in platelets and leucocytes.
View Article and Find Full Text PDFImpact of perceived discrimination and coping strategies on well-being and mental health in newly-arrived migrants in Spain.
PLoS One
December 2023
Teaching, Research & Innovation Unit, Parc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, Barcelona, Spain.
Objectives: To explore how perceived discrimination impacts the emotional well-being and mental health of newly-arrived migrants in Spain; and to identify the coping strategies and behavioral changes used to deal with perceived discrimination.
Design: 102 individual audio-recorded in-depth qualitative interviews were conducted. The interviews were transcribed and analyzed through content analysis.
Fighting rages in Sudan-its people and their healthcare pay the price.
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Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
The study of chemical components in Qishiwei Zhenzhu pills and its anti-apoptotic mechanism in cerebral ischemic based on LC-MS and network pharmacology.
J Ethnopharmacol
February 2023
College of Ethnomedicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China. Electronic address:
Ethnopharmacological Relevance: Qishiwei Zhenzhu pills are one of the most representative precious treasure proprietary medicines and have been used for nearly 500 years in clinical practice in Chinese. This medicine can prevent diseases and play a certain role in fighting altitude sickness with cerebral ischemia.
Aim Of The Study: This study used LC-MS to analyse the chemical constituents of Qishiwei Zhenzhu pills, which laid a foundation for the improvement of the quality standard and the basic research of pharmacodynamics substances.
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