"Safe Supply" Initiatives: Are They a Recipe for Harm Through Reduced Health Care Input and Supply-Induced Toxicity and Overdose?

J Stud Alcohol Drugs

Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford University, Stanford, California.

Published: July 2023

Within the addiction field, some advocates support a suite of de-regulatory policies that aim to reduce harm by providing people who use drugs with a "safe supply" of pharmaceutical-grade medications. Such initiatives have commenced without the evidence standards normally used to label medication provision as "safe." This perspective suggests that continued debate and research in this area acknowledge the potential toxicity of any provided safe supply medications and highlights that these initiatives could result in an unhelpful reduction in interactions between people who use drugs and health care professionals.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488309PMC
http://dx.doi.org/10.15288/jsad.23-00054DOI Listing

Publication Analysis

Top Keywords

"safe supply"
8
health care
8
people drugs
8
supply" initiatives
4
initiatives recipe
4
recipe harm
4
harm reduced
4
reduced health
4
care input
4
input supply-induced
4

Similar Publications

Due to the spread of SARS-CoV-2 virus infectious disease (COVID-19), blood donation events had to be cancelled, and there were concerns about a decrease in the number of blood donors from late February 2020 in Japan. The purpose of this study is to investigate the numbers of whole blood donation, manufacture and inventory adjustment of red blood cell (RBC) products at the Japanese Red Cross Society (JRCS), and to evaluate the effects of COVID-19 on the donation of blood and the supply of RBC products to medical institutions for transfusion medicine in Japan. We focused on RBC products, which are the most frequently used blood products and are easily reflected under the spread of COVID-19.

View Article and Find Full Text PDF

City gas stations (CGSs) play a crucial role in ensuring a stable and safe supply of natural gas to urban users. However, as the service time of stations increases and the performance of components deteriorates, concerns about the safety and reliability of these station have grown among operators and local government authorities. This paper proposes a fuzzy reliability assessment methodology for CGSs that considers the polymorphism of component faults and the uncertainties associated with fault relationships, failure probabilities, and fault magnitudes.

View Article and Find Full Text PDF

The proteasome is considered an excellent drug target for many infectious diseases as well as cancer. Challenges with robust and safe supply of proteasomes from infectious agents, lack of structural information, and complex pharmacology due to multiple active sites have hampered progress in the infectious disease space. We recombinantly expressed the proteasome of the protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease, and demonstrate pharmacological equivalence to the native T.

View Article and Find Full Text PDF

Misrepresentation of MDMA in the United States, 1999-2023.

Drug Alcohol Depend

November 2024

Department of Criminal Justice and Criminology, Georgia State University, Atlanta, GA, USA.

Background And Aims: The misrepresentation of illicit drugs in unregulated markets increases the risk of adverse health events. This study analyzed drug checking data to compare represented, expected, and actual content of alleged MDMA samples, estimate trends in the quality of the MDMA supply, document the presence of adulterants, compare patterns of adulteration, and validate drug checking against law enforcement data.

Method: The study analyzed 4719 alleged MDMA samples submitted to the DrugsData drug checking service between 1999-2023.

View Article and Find Full Text PDF
Article Synopsis
  • Blood transfusion services are essential in healthcare, focusing on the identification of seropositive blood donors to enhance the safety of transfusion practices.
  • A study spanning 24 months at a southern Indian hospital found that out of 8,276 donations, 117 (1.41%) tested reactive for transfusion-transmitted infections, with hepatitis B being the most prevalent at 0.61%.
  • It was revealed that 70% of reactive donors were contacted post-donation, but challenges like inaccurate addresses hindered follow-up, emphasizing the need for accurate information from donors and the importance of post-donation counseling.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!