This article explains the puzzle why subjective well-being (SBW) declined in Kazakhstan and increased in Kyrgyzstan from 2011 to 2018. It examined the predictors of the change in SWB in two Central Asian states over this period. We found that freedom of choice and financial satisfaction are powerful factors that predict the change in SWB in the two states. In addition, we observed that SWB has changed differently for various social groups. In Kazakhstan SWB has increased for financially satisfied people and it has diminished for the financially dissatisfied people. In Kyrgyzstan, for both groups we observe the increase in life satisfaction. These results show that even within one state the change in SWB might vary from one group to another. As such, scholars should disaggregate various factors to understand a more nuanced dynamics of life satisfaction over time. In addition, the differences in economic and political contexts are important.
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http://dx.doi.org/10.1007/s10902-022-00607-1 | DOI Listing |
Nat Commun
January 2025
Department of Civil and Environmental Engineering, University of Waterloo, Waterloo, ON, N2L 3G1, Canada.
Climate change, population growth, and agricultural intensification are increasing nitrogen (N) inputs, while driving the loss of inland water bodies that filter excess N. However, the interplay between N inputs and water body dynamics, and its implications for water quality remain poorly understood. Analyzing data from 1995 to 2015 across China, here, we find a 71% reduction in the area of small (<10 m) water bodies (SWB), primarily in high-N-input agricultural regions.
View Article and Find Full Text PDFElife
December 2024
Birmingham Centre for Neurogenetics, School of Biosciences, University of Birmingham, Birmingham, United Kingdom.
Experience shapes the brain as neural circuits can be modified by neural stimulation or the lack of it. The molecular mechanisms underlying structural circuit plasticity and how plasticity modifies behaviour are poorly understood. Subjective experience requires dopamine, a neuromodulator that assigns a value to stimuli, and it also controls behaviour, including locomotion, learning, and memory.
View Article and Find Full Text PDFBMC Public Health
December 2024
Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Background: We aimed to assess the effects of body mass index (BMI), activities of daily living (ADL), and subjective well-being (SWB) on cognitive impairment and propose dynamic risk prediction models for aging cognitive decline.
Methods: We leveraged the Chinese Longitudinal Healthy Longevity Survey from 1998 to 2018. Cognitive status was measured using the Chinese Mini-Mental State Examination.
Biochem Biophys Res Commun
January 2025
Institute of Chemical Biology and Fundamental Medicine, SB RAS, 630090, Novosibirsk, Russia; Novosibirsk State University, 630090, Novosibirsk, Russia. Electronic address:
The thermodynamics of interactions between Cas12a, RNA, and DNA are important to understanding the molecular mechanisms governing CRISPR-Cas12a's specificity and function. In this study, we employed isothermal titration calorimetry (ITC) and molecular dynamics (MD) simulations to investigate the binding properties and energetic contributions of Cas12a-crRNA complexes with single-stranded (ssDNA) and double-stranded (dsDNA) DNA substrates. ITC analyses revealed significant thermal effects during the interaction of Cas12a-crRNA with ssDNA but no detectable effects with dsDNA.
View Article and Find Full Text PDFAnimals (Basel)
December 2024
Science and Conservation Center, 2100 South Shiloh Road, Billings, MT 59106, USA.
Wildlife managers and the public have expressed considerable interest in the use of contraception to help manage the populations of wild horses and burros ( and ). Field testing has shown that two preparations of the porcine zona pellucida (PZP) vaccine, a simple emulsion (ZonaStat-H) and PZP-22 (which supplements ZonaStat-H with a controlled-release component) effectively prevent pregnancy in individual mares and can substantially reduce population foaling rates. To determine whether some PZP preparations might have secondary effects that harm treated mares or their foals, we examined the effects of PZP-22 vaccinations and the follow-up boosters of either PZP-22 or ZonaStat-H on adult female body condition, foaling season, and foal mortality in two wild horse herds in the western USA, Cedar Mountains Herd Management Area, Utah (CM; 2008-2015), and Sand Wash Basin Herd Management Area, Colorado (SWB; 2008-2014).
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