Fungemia is a fatal systemic infection that can occur in immunocompromised patients. Despite that, antifungal stewardship is spreading widely, but the mortality rate is extremely high, showing 40-60%. is a newly morphologically detected pathogen, first described in 1994, followed by isolation in humans in 2008. It has been misrecognized as . Recently, fever attributable to fungemia cases has been reported, and the etiology and clinical features are still unknown. Here, we present three successfully treated fungemia cases by echinocandin. In total, 11 cases were reviewed, including ours. Six of the eleven cases (55%) had external devices. All cases had some immunocompromised conditions or underlying diseases, such as diabetes mellitus, lung cancer, etc. Six patients survived, and the remaining five died. Seven patients who had received echinocandin initially survived. Risk factors for fungemia overlap with those of candidemia. Even though there is no breakpoint for , echinocandin can be a helpful treatment regimen for fungemia.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142367 | PMC |
http://dx.doi.org/10.3390/microorganisms11041076 | DOI Listing |
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