AI Article Synopsis

  • * A newly identified pathogen linked to fungemia has been misidentified in the past, and while recent cases show fever symptoms, the specific causes and clinical aspects remain unclear.
  • * A review of 11 treated cases highlighted that echinocandin, an antifungal treatment, was effective for those who received it initially, with a survival rate of 55% among patients with underlying health issues like diabetes or lung cancer.

Article Abstract

Fungemia is a fatal systemic infection that can occur in immunocompromised patients. Despite that, antifungal stewardship is spreading widely, but the mortality rate is extremely high, showing 40-60%. is a newly morphologically detected pathogen, first described in 1994, followed by isolation in humans in 2008. It has been misrecognized as . Recently, fever attributable to fungemia cases has been reported, and the etiology and clinical features are still unknown. Here, we present three successfully treated fungemia cases by echinocandin. In total, 11 cases were reviewed, including ours. Six of the eleven cases (55%) had external devices. All cases had some immunocompromised conditions or underlying diseases, such as diabetes mellitus, lung cancer, etc. Six patients survived, and the remaining five died. Seven patients who had received echinocandin initially survived. Risk factors for fungemia overlap with those of candidemia. Even though there is no breakpoint for , echinocandin can be a helpful treatment regimen for fungemia.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142367PMC
http://dx.doi.org/10.3390/microorganisms11041076DOI Listing

Publication Analysis

Top Keywords

three treated
8
fungemia cases
8
cases
6
fungemia
6
treated cases
4
cases fungemia
4
fungemia case
4
case reports
4
reports review
4
review literature
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!