Background: Collateral damage to surrounding healthy tissues has been reported in patients who undergo radiation therapy for pelvic malignancies. This study aimed to evaluate the safety, efficacy and cost efficiency of endoscopic diode laser therapy in patients diagnosed with chronic radiation proctitis (CRP).
Methods: The data of 24 patients (median age 78, range 67-90 years) who presented rectal bleeding and were diagnosed with CRP after undergoing high-dose radiotherapy for prostatic cancer and underwent diode laser therapy were evaluated retrospectively. Non-contact fibers were used in the patients who underwent the procedure without sedation in an outpatient setting.
Results: The patients underwent a median of two sessions; overall, a mean of 1591 J of laser energy per session was used. No complications were noted during or after the procedures. Bleeding was completely resolved in 21/24 (88%) patients, and two patients showed improvement (96%). It was not necessary to suspend antiplatelet (six patients) or anticoagulant (four patients) therapy during the treatment course. The mean cost per session was EUR 473.4.
Conclusions: The study findings demonstrated that endoscopic non-contact diode laser treatment in CRP patients is safe, effective and cost efficient. For this procedure, antiplatelet and anticoagulant therapy suspension, intraprocedural sedation and hospital admission are not required.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144337 | PMC |
| http://dx.doi.org/10.3390/life13041025 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Efficacy of non -thermal pressure plasma versus other modalities for disinfection of primary root canals.
BMC Oral Health
January 2025
Associate Professor of Operative Dentistry, Conservative Dentistry Department, Faculty of Oral and Dental Medicine Badr University in Cairo, Cairo, Egypt.
Background: Endodontic treatment aims in the preservation of extremely carious primary teeth. For root canal therapy to be successful, root canals must be properly prepared and effectively irrigated .Therefore, it is necessary to select the proper root canal disinfection method to preserve the primary tooth.
View Article and Find Full Text PDFMolecular evidence for the efficacy of PBM therapy in the treatment of Oral lichen planus.
Photodiagnosis Photodyn Ther
January 2025
Department of Healthcare and Social Work, New Bulgarian University, Sofia, Bulgaria. Electronic address:
Purpose: Oral lichen planus (OLP) is a chronic inflammatory disease, in which T-Lymphocytes induce apoptosis of basal keratinocytes, leading to the formation of symptomatic lesions. It is assumed that blocking the cell death program and enhancing cell proliferation would be crucial to the healing process. The aim of the study was to verify the efficacy of Photobiomodulation (PBM) in OLP management, by evaluating the effects of laser irradiation on the processes of apoptosis and cell proliferation.
View Article and Find Full Text PDFEfficacy of non-surgical mechanical debridement with and without adjunct antimicrobial photodynamic therapy in the treatment of peri-implantitis among patients undergoing chemotherapy.
Photodiagnosis Photodyn Ther
January 2025
Department of Oral Maxillofacial Radiologist, Department of OMFS & DOS College of Medicine and Dentistry, Riyadh Elm University, Saudi Arabia.
Article Synopsis
- The study aimed to evaluate the effectiveness of antimicrobial photodynamic therapy (aPDT) combined with mechanical debridement (MD) in treating peri-implantitis in patients undergoing chemotherapy compared to systemically healthy patients.
- Both patient groups were assessed; however, results showed no significant differences in key measurements (plaque and gingival indices, probing depth, and bone loss) between the two groups at both baseline and three-month follow-up.
- Overall, the findings indicated that adding aPDT to MD did not lead to enhanced treatment outcomes for peri-implantitis in either chemotherapy patients or systemically healthy individuals.
Evaluating the efficacy of cavity disinfection using methylene blue dye with 660-nm diode laser on primary molars: An in vivo study.
J Indian Soc Pedod Prev Dent
October 2024
Department of Pediatric and Preventive Dentistry, Maratha Mandal's Nathajirao G. Halgekar Institute of Dental Sciences and Research Centre, Belagavi, Karnataka, India.
Background And Objectives: The purpose of this study was to evaluate the antimicrobial activity of methylene blue dye with 660-nm diode laser in cavity disinfection and to compare the total bacterial count in dentinal samples preexcavation, postexcavation, and postdisinfection. The study design was experimental in vivo.
Materials And Methods: Fifteen children aged 5-12 years with 15 primary molars requiring atraumatic restorative treatment (ART) were selected.
Research Progress in Fiber Bragg Grating-Based Ocean Temperature and Depth Sensors.
Sensors (Basel)
December 2024
College of Physics and Electronic Engineering, Hainan Normal University, Haikou 571158, China.
Fiber Bragg gratings (FBGs) are widely used in stress and temperature sensing due to their small size, light weight, high resistance to high temperatures, corrosion, electromagnetic interference, and low cost. In recent years, various structural enhancements and sensitization to FBGs have been explored to improve the performance of ocean temperature and depth sensors, thereby enhancing the accuracy and detection range of ocean temperature and depth data. This paper reviews advancements in temperature, pressure, and dual-parameter enhancement techniques for FBG-based sensors.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!