The Role of Yeasts in Human Health: A Review.

Life (Basel)

CICS-UBI-Health Sciences Research Center, Faculty of Health Sciences, University of Beira Interior, 6200-506 Covilhã, Portugal.

Published: March 2023

AI Article Synopsis

  • The microbiome is mainly composed of bacteria, but recent research shows that fungi significantly contribute to human health and the stability of the microbiota.
  • While we are learning more about the role of commensal fungi in various body systems like the gut and skin, more research is still needed to fully understand their functions.
  • Current studies primarily focus on fungal diseases, leaving the beneficial roles fungi play in the microbiota somewhat unexplored; this review summarizes what we know about yeasts that are part of the human body and the diseases they can cause when the microbiota is disrupted.

Article Abstract

The microbiome consists mostly of bacteria, but new evidence and developments in sequencing methods have shown that fungi play an important role in human health and in the stability of the microbiota. Scientific knowledge about the role of commensal fungi in intestinal, oral, vaginal and cutaneous communities has been increasing; however, more studies are still needed to better understand their action in these niches. To date, fungal research focuses primarily on opportunistic diseases caused by fungal species, leaving unclear the possible role of fungi as an integral part of the microbiota. Although they are much less abundant than bacteria, fungi such as species belonging to the genus , , and are some of the yeasts that have been in the focus of the scientific community because they inhabit various niches. In this review, we have summarized the current information about the yeasts that inhabit the human body, including some of the diseases that they can cause when the microbiota becomes unstable.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143383PMC
http://dx.doi.org/10.3390/life13040924DOI Listing

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