Characterization and Genome Analysis of , the Causal Agent of Cobweb Disease of in China.

J Fungi (Basel)

Engineering Research Center of Edible and Medicinal Fungi, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.

Published: March 2023

AI Article Synopsis

  • Cobweb disease, a fungal threat to edible mushrooms, was investigated in Guizhou Province, China, where the pathogen causing the disease was isolated and identified for the first time.
  • Using HiFi sequencing, researchers generated a high-quality genome assembly of the pathogen, revealing 8428 protein-coding genes related to its disease-causing mechanisms.
  • The study provides crucial insights into the pathogen's biology and opens up possibilities for developing prevention and control measures against cobweb disease.

Article Abstract

Cobweb disease is a fungal disease that can cause serious damage to edible mushrooms worldwide. To investigate cobweb disease in in Guizhou Province, China, we isolated and purified the pathogen responsible for the disease. Through morphological and molecular identification and pathogenicity testing on infected . , we identified as the cause of cobweb disease in this region. This is the first known occurrence of this pathogen causing cobweb disease in . anywhere in the world. We then obtained the genome of . BJWN07 using the HiFi sequencing platform, resulting in a high-quality genome assembly with a size of 38.56 Mb, 10 contigs, and a GC content of 47.84%. We annotated 8428 protein-coding genes in the genome, including many secreted proteins, host interaction-related genes, and carbohydrate-active enzymes (CAZymes) related to the pathogenesis of the disease. Our findings shed new light on the pathogenesis of . and provide a theoretical basis for developing potential prevention and control strategies for cobweb disease.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145569PMC
http://dx.doi.org/10.3390/jof9040411DOI Listing

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