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Occult collision tumor of the gastroesophageal junction comprising adenocarcinomas with distinct molecular profiles.
Cancer Genet
January 2025
Department of Pathology and Laboratory Medicine, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA; Rutgers Cancer Institute, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.
Collision tumors, characterized by the coexistence of two unique neoplasms in close approximation, are rare and pose diagnostic challenges. This is particularly true when the unique neoplasms are of the same histologic type. Here we report such a case where comprehensive tumor profiling by next generation sequencing (NGS) as well as immunohistochemistry revealed two independent adenocarcinomas comprising what was initially diagnosed as a single adenocarcinoma of the gastroesophageal (GEJ) junction.
View Article and Find Full Text PDFRecurrent adamantinomatous craniopharyngioma stabilized with tocilizumab and bevacizumab: illustrative case.
J Neurosurg Case Lessons
January 2025
Department of Neurology, Mayo Clinic, Rochester, Minnesota.
Background: Adamantinomatous craniopharyngiomas (ACPs) are slow-growing, cystic, highly morbid central nervous system tumors located adjacent to vital structures including the pituitary, hypothalamus, and optic chiasm. Tumor recurrence is common. Treatment relies on resection with or without adjuvant radiation and is highly individualized.
View Article and Find Full Text PDFHigh-Pressure Refrigerant Gas Injection Injury to the Hand.
J Am Acad Orthop Surg Glob Res Rev
January 2025
From the Department of Orthopaedics and Sports Medicine, Mercy Health St. Vincent Medical Center, Toledo, OH (Dr. Simmons); the Department of Orthopedic Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH (Dr. Vesselle); the Department of Orthopaedic Surgery, MetroHealth Medical Center, Cleveland, OH (Dr. Yildirim, Dr. Bafus); the Town Center Orthopaedics, Reston, VA (Dr. Yildirim); and the Louis Stokes Cleveland VA Medical Center, Cleveland, OH (Dr. Bafus).
High-pressure injection injuries, although rare, are commonly discussed orthopaedic surgical emergencies. In many cases, high-pressure injection injuries can have detrimental effects on the patient. However, there are rare instances where surgical intervention may be more harmful than helpful.
View Article and Find Full Text PDFSuperficial basal cell carcinoma masquerading as pruritic dermatitis on the upper eyelid.
Acta Dermatovenerol Alp Pannonica Adriat
January 2025
Regional Hospital of Trujillo, Trujillo, Peru.
Although basal cell carcinoma is the most common form of skin cancer, the superficial subtype is rarely seen on the upper eyelid. We report the case of a 71-year-old woman with a 4-year history of upper eyelid pruritus, initially diagnosed as blepharitis and unsuccessfully treated with various medications, including topical and systemic corticosteroids, topical immunomodulators, and antihistamines. The unusual presentation, location, histologic subtype, and persistent pruritus posed a significant diagnostic challenge in this case.
View Article and Find Full Text PDFVentricular fibrillation likely resulting from electrocautery and amiodarone: a rare clinical case report.
J Int Med Res
January 2025
Department of Anesthesiology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
Monopolar electrocautery is usually a safe and effective technique used in laparoscopic cholecystectomy and bile duct surgery, but it may lead to adverse consequences, even ventricular fibrillation (VF). Amiodarone is an effective antiarrhythmic drug commonly used in practice to treat ventricular and atrial arrhythmias, but it may induce tachyarrhythmia or even VF. We report a case of VF occurring twice during cholecystectomy.
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