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http://dx.doi.org/10.3399/bjgp23X732561 | DOI Listing |
PLoS Biol
January 2025
Department of Cell and Systems Biology, University of Toronto, Toronto, Canada.
Successful resolution of approach-avoidance conflict (AAC) is fundamentally important for survival, and its dysregulation is a hallmark of many neuropsychiatric disorders, and yet the underlying neural circuit mechanisms are not well elucidated. Converging human and animal research has implicated the anterior/ventral hippocampus (vHPC) as a key node in arbitrating AAC in a region-specific manner. In this study, we sought to target the vHPC CA1 projection pathway to the nucleus accumbens (NAc) to delineate its contribution to AAC decision-making, particularly in the arbitration of learned reward and punishment signals, as well as innate signals.
View Article and Find Full Text PDFSci Adv
January 2025
Doerr School of Sustainability, Stanford University, Stanford, CA, USA.
Poor ambient air quality poses a substantial global health threat. However, accurate measurement remains challenging, particularly in countries such as India where ground monitors are scarce despite high expected exposure and health burdens. This lack of precise measurements impedes understanding of changes in pollution exposure over time and across populations.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Educational Leadership and Policies, College of Education, Taif University, Taif, Kingdom of Saudia Arabia.
This study examined the relationship between institutional support and student engagement in e-learning, with time efficiency as a potential mediator among Saudi university students. This study employed a cross-sectional, questionnaire-based research design. A sample of 752 Saudi university students from different provinces in the Kingdom of Saudi Arabia completed an online questionnaire.
View Article and Find Full Text PDFCell Rep
January 2025
Department of Psychology, University of Oregon, Eugene, OR, USA.
More than a century of research shows that spaced learning improves long-term memory. However, there remains debate concerning why that is. A major limitation to resolving theoretical debates is the lack of evidence for how neural representations change as a function of spacing.
View Article and Find Full Text PDFImmun Inflamm Dis
January 2025
Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China.
Background: Long COVID, a heterogeneous condition characterized by a range of physical and neuropsychiatric presentations, can be presented with a proportion of COVID-19-infected individuals.
Methods: Transcriptomic data sets of those within gene expression profiles of COVID-19, long COVID, and healthy controls were retrieved from the GEO database. Differentially expressed genes (DEGs) falling under COVID-19 and long COVID were identified with R packages, and contemporaneously conducted module detection was performed with the Modular Pharmacology Platform (http://112.
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