This investigation was conducted to determine how the growth and carcass traits of meat-type sheep breeds raised in Turkey are associated with 5'UTR polymorphisms. Overall, 202 lambs from five breeds were evaluated. We identified eight nucleotide changes (seven substitutions and one deletion) in three variants of 5'UTR by SSCP analysis and nucleotide sequencing. It was found that the variants had a unique deletion (g.171328230 delT), while the variants were identified by SNPs rs401028781, rs422604851, and g.171328404C > Y. The variants possessed one heterozygous substitution (g.171328260G > R) and three homozygous substitutions (g.171328246T > A, g.171328257T > G, g.171328265T > C) not observed in or . Based on the growth and production traits, a statistically significant difference was found only in chest width at weaning ( < 0.01) and leg circumferences at yearling ( < 0.05). The variants showed a leaner profile with a higher but the differences were not significant ( > 0.05). The variants had a higher percentage of rack ( < 0.01) and loin ( > 0.05). Moreover, there was no discernible difference between variants, even though the variants had a higher percentage of neck and leg and the variants had a higher percentage of the shoulder. It is concluded that nucleotide changes in 5'UTR could be exploited utilizing a marker-assisted selection technique to increase growth and production attributes, as well as carcass quality traits.
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| http://dx.doi.org/10.3390/vetsci10040270 | DOI Listing |
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