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Characterization of the Disorganization of the Inner Retinal Layers in Diabetics Using Increased Axial Resolution Optical Coherence Tomography.
Transl Vis Sci Technol
January 2025
Department of Ophthalmology, University Hospital Bonn, Bonn, Germany.
Purpose: To compare a novel high-resolution optical coherence tomography (OCT) with improved axial resolution (High-Res OCT) with conventional spectral-domain OCT (SD-OCT) with regard to their capacity to characterize the disorganization of the retinal inner layers (DRIL) in diabetic maculopathy.
Methods: Diabetic patients underwent multimodal retinal imaging (SD-OCT, High-Res OCT, and color fundus photography). Best-corrected visual acuity and diabetes characteristics were recorded.
Analysis of Giant-Shell CdSe/CdS Quantum Dots via Analytical Ultracentrifugation Combined with Spectrally Resolved Photoluminescence.
Small Methods
January 2025
Institute of Particle Technology (LFG), Department of Chemical and Biological, Engineering (CBI), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Cauerstraße 4, 91058, Erlangen, Germany.
Knowledge of the structure-property relationships of functional nanomaterials, including, for example, their size- and composition-dependent photoluminescence (PL) and particle-to-particle variations, is crucial for their design and reproducibility. Herein, the Angstrom-resolution capability of an analytical ultracentrifuge combined with an in-line multiwavelength emission detection system (MWE-AUC) for measuring the sedimentation coefficient-resolved spectrally corrected PL spectra of dispersed nanoparticles is demonstrated. The capabilities of this technique are shown for giant-shell CdSe/CdS quantum dots (g-QDs) with a PL quantum yield (PL QY) close to unity capped with oleic acid and oleylamine ligands.
View Article and Find Full Text PDFTablet diversion strategy based on in-line NIR tablet press feed frame measurements.
Int J Pharm
January 2025
Pharmaceutical Engineering Research Group (PharmaEng), Department of Pharmaceutical Analysis, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium. Electronic address:
The tablet diversion strategy, based on in-line near-infrared (NIR) tablet press feed frame measurements, can be a key component of both batch and continuous oral solid dose manufacturing processes. It enables real-time, high-frequency monitoring and control, enhancing process understanding and compliance compared to conventional interval-based sampling methods. Central to this strategy are NIR spectrometers, which serve as PAT systems for in-line blend uniformity monitoring in the feed of the tablet press.
View Article and Find Full Text PDFArtificial intelligence with wrapper multioutput regression to identify chemical contents of fresh and dried manure samples using NIR spectroscopy.
Spectrochim Acta A Mol Biomol Spectrosc
January 2025
School of Physical and Applied Sciences, Goa University, Taleigao Plateau, Goa 403206, India. Electronic address:
Analyzing manure nutrients such as total ammonium nitrogen (NH), dry matter (DM), calcium oxide (CaO), total nitrogen (-N), phosphorus pentoxide (PO), magnesium oxide (MgO), and potassium oxide (KO) helps in fulfilling crop nutritional needs while improving the profitability and a lower risk of pollutants. This study used two Near Infra Red (NIR) spectral datasets of fresh and dried manure. The freshly prepared NHCl, CaO, Ca(OH), PO, MgO, and KO samples were used for spectral signature peak identification and calibration.
View Article and Find Full Text PDFA Comparative Analysis of the Effects of Misaligning Different Trifocal Intraocular Lenses.
J Clin Med
December 2024
The David J Apple Center for Vision Research, Department of Ophthalmology, Heidelberg University Eye Clinic, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.
This laboratory study aims to assess the effects of misaligning different trifocal intraocular lenses (IOLs) under varying spectral and corneal spherical aberration (SA) conditions. With an IOL metrology device under monochromatic and polychromatic conditions, the following models were studied: AT ELANA 841P, AT LISA Tri 839MP, FineVision HP POD F, Acrysof IQ PanOptix, and Tecnis Synergy ZFR00V. The SA was simulated using an aberration-free and average-SA cornea.
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