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| http://dx.doi.org/10.4103/jips.jips_131_23 | DOI Listing |
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Basal metabolic rate correlates with excess postexercise oxygen consumption across different intensities.
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January 2025
Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital-Linkou, Chang Gung University College of Medicine, Taoyuan, 33302, Taiwan.
Background: Both the basal metabolic rate (BMR) and excess postexercise oxygen consumption (EPOC) can be influenced by physical training and are associated with body composition and aerobic capacity. Although a correlation between the two is expected, this relationship has not been explored. Our hypothesis is that a higher BMR is correlated with lower EPOC.
View Article and Find Full Text PDFComputational modeling design of novel NMDAR agonist for the treatment of Schizophrenia.
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Department of Biochemistry, College of Medicine, University of Lagos, Lagos State, Nigeria.
Schizophrenia (SZ) is a complex, chronic mental disorder characterized by positive symptoms (such as delusions and hallucinations), negative symptoms (including anhedonia, alogia, avolition, and social withdrawal), and cognitive deficits (affecting attention, processing speed, verbal and visuospatial learning, problem-solving, working memory, and mental flexibility). Extensive animal and clinical studies have emphasized the NMDAR hypofunction hypothesis of SZ. Glycine plays a crucial role as an agonist of NMDAR, enhancing the receptor's affinity for glutamate and supporting normal synaptic function and plasticity, that is, signal transmission between neurons.
View Article and Find Full Text PDFApplication of urinary peptide-biomarkers in trauma patients as a predictive tool for prognostic assessment, treatment and intervention timing.
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Department of Trauma Surgery, Hannover Medical School, Carl-Neuberg St. 1, 30625, Hannover, Lower Saxony, Germany.
Treatment of severely injured patients represents a major challenge, in part due to the unpredictable risk of major adverse events, including death. Preemptive personalized treatment aimed at preventing these events is a crucial objective of patient management; however, the currently available scoring systems provide only moderate guidance. Biomarkers from proteomics/peptidomics studies hold promise for improving the current situation, ultimately enabling precision medicine based on individual molecular profiles.
View Article and Find Full Text PDFEscitalopram reverses anxiety-like and despair behavior and affects endocannabinoid-related genes expression in the brain of adolescent male rats subjected to early life stress.
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Department of Pharmacology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medyków 18, 40-752 Katowice, Poland. Electronic address:
Due to the increasing prevalence of depressive and anxiety disorders in youth, a growing interest in the endocannabinoid system (ECS) as a potential alternative target point for treatment arised. This study aimed to investigate whether chronic administration of escitalopram reverses behavioral changes induced by maternal separation in male adolescent Wistar rats and explore the corresponding neurochemical changes in the ECS. The pups were separated from their dams for 360 min daily from postnatal day (PND) 2 until PND 15.
View Article and Find Full Text PDFThe power of music: impact on EEG signals.
Psychol Res
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Department of Neurology and Clinical Neurophysiology Unit, Faculty of Medicine-Cairo University, Cairo, Egypt.
Introduction: Music is known to impact attentional state without conscious awareness. Listening to music encourages the brain to secrete neurotransmitters improving cognition and emotion.
Aim Of Work: Analysis of QEEG band width while listening to two music types, identifying different cortical areas activated and which genre has a similar effect to relaxed EEG.
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