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Severe Ethylene Glycol Toxicity: Multidisciplinary Management and Long-Term Renal Implications.
Cureus
December 2024
Internal Medicine, Griffin Hospital, Derby, USA.
Ethylene glycol (C₂H₆O₂), a toxic alcohol commonly found in automotive antifreeze, de-icing solutions, and industrial coolants, can cause severe toxicity when ingested. Due to its sweet taste, it is often consumed accidentally or intentionally, leading to life-threatening consequences such as metabolic acidosis, acute kidney injury (AKI), and mortality. Prompt diagnosis and early treatment with antidotes such as fomepizole or ethanol, combined with hemodialysis, are essential in preventing severe outcomes.
View Article and Find Full Text PDFA Triangular Frustrated Eu(II)-Organic Framework for Sub-Kelvin Magnetic Refrigeration.
J Am Chem Soc
January 2025
Department of Chemistry, Technical University of Denmark, DK-2800 Kongens Lyngby, Denmark.
Attaining sub-Kelvin temperatures remains technologically challenging and often relies on the scarce resource He, unless employing adiabatic demagnetization refrigeration. Herein, the active coolant typically consists of weakly coupled paramagnetic ions, whose magnetic interaction strengths are comparable in energy to the relevant temperature regime of cooling. Such interactions depend strongly on inter-ion distances, fundamentally hindering the realization of dense coolants for sub-Kelvin refrigeration.
View Article and Find Full Text PDFRecommendations for mitochondria transfer and transplantation nomenclature and characterization.
Nat Metab
January 2025
Centre for Orthopaedic Research, Medical School of the University of Western Australia, Nedlands, Western Australia, Australia.
Intercellular mitochondria transfer is an evolutionarily conserved process in which one cell delivers some of their mitochondria to another cell in the absence of cell division. This process has diverse functions depending on the cell types involved and physiological or disease context. Although mitochondria transfer was first shown to provide metabolic support to acceptor cells, recent studies have revealed diverse functions of mitochondria transfer, including, but not limited to, the maintenance of mitochondria quality of the donor cell and the regulation of tissue homeostasis and remodelling.
View Article and Find Full Text PDFOptimization of MoNiCr Alloy Production Through Additive Manufacturing.
Materials (Basel)
December 2024
COMTES FHT a.s., Prumyslova 995, 334 41 Dobrany, Czech Republic.
One of the concepts behind Generation IV reactors is a molten salt coolant system, where the materials for the reactor itself and for the primary and secondary circuit components are subjected to extreme chemical and thermal stresses. Due to the unavailability of these materials, a nickel-molybdenum alloy known as MoNiCr has been developed in the Czech Republic. This paper discusses the manufacturing process for the MoNiCr alloy, covering conventional casting technology, forming, powder atomization, additive manufacturing (AM) using the directed energy deposition (DED-LB) process, and final heat treatment.
View Article and Find Full Text PDFThe Effect of Absorbed Hydrogen on the Rotors of Steel Machining Products During Powerful Turbo Aggregate Repairs.
Materials (Basel)
December 2024
Department of Strength of the Materials and Structures in Hydrogen-Containing Environments, Karpenko Physico-Mechanical Institute, National Academy of Sciences of Ukraine, 5 Naukova Str., 79601 Lviv, Ukraine.
Rotor shafts are the most heavily loaded and accident-prone parts of powerful turbine generators, which are cooled using hydrogen. To eliminate damage sustained during operations, repair work was carried out, including the removal of defective parts, surfacing, and turning. This study tested the machinability of the rotor shaft using prototypes made from 38KhN3MFA steel.
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