Researchers conduct meta-analyses in order to synthesize information across different studies. Compared to standard meta-analytic methods, Bayesian model-averaged meta-analysis offers several practical advantages including the ability to quantify evidence in favor of the absence of an effect, the ability to monitor evidence as individual studies accumulate indefinitely, and the ability to draw inferences based on multiple models simultaneously. This tutorial introduces the concepts and logic underlying Bayesian model-averaged meta-analysis and illustrates its application using the open-source software JASP. As a running example, we perform a Bayesian meta-analysis on language development in children. We show how to conduct a Bayesian model-averaged meta-analysis and how to interpret the results.
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http://dx.doi.org/10.3758/s13428-023-02093-6 | DOI Listing |
Medicine (Baltimore)
December 2024
Brain Disease Center, The First Affiliated Hospital of Henan College of Traditional Chinese Medicine, Zhengzhou, China.
The study investigates the causal relationship between gut microbes and female genital tract polyps, exploring the potential mediating role of immune cells via Mendelian randomization (MR) analysis. Our MR study was designed following the STROBE-MR guidelines. We combined data from a large-scale GWAS meta-analysis, including 731 immune profiles and female genital tract polyps, with gut microbiology data sourced from the MiBioGen consortium.
View Article and Find Full Text PDFEnviron Pollut
November 2024
Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address:
The association between exposure to perchlorate, which inhibits thyroidal iodine uptake, and cardiovascular disease (CVD) is unclear in China. Moreover, the point of departure (POD) for perchlorate based on observed adverse health effect in Chinese populations remains absent. A total of 2355 adults (mean age 50.
View Article and Find Full Text PDFPsychon Bull Rev
November 2024
Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands.
One of the most common statistical analyses in experimental psychology concerns the comparison of two means using the frequentist t test. However, frequentist t tests do not quantify evidence and require various assumption tests. Recently, popularized Bayesian t tests do quantify evidence, but these were developed for scenarios where the two populations are assumed to have the same variance.
View Article and Find Full Text PDFJ Cardiovasc Magn Reson
December 2024
Department of Laboratory and Transfusion Medicine, University of Occupational and Environmental Health Hospital, Kitakyushu, Japan.
Nutrients
September 2024
Department of Epidemiology, School of Public Health, Southern Medical University, Guangzhou 510515, China.
: The causal association of specific gut microbiota with dementia remains incompletely understood. We aimed to access the causal relationships in which one or more gut microbiota account for dementia. : Using data from the MiBioGen and FinnGen consortia, we employed multiple Mendelian randomization (MR) approaches including two-sample MR (TSMR), multivariable MR (MVMR), and Bayesian model averaging MR to comprehensively evaluate the causal associations between 119 genera and dementia, and to prioritize the predominant bacterium.
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