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Prevalence of Diabetes in Patients with Hyperuricemia and Gout: A Systematic Review and Meta-analysis. | LitMetric

AI Article Synopsis

  • * A meta-analysis of 38 studies found that the prevalence of diabetes in patients with hyperuricemia is 19.10%, while it's 16.70% for those with gout, with higher rates observed in North America.
  • * Older patients and those on diuretics exhibited a greater prevalence of diabetes; thus, managing both uric acid and glucose levels is essential for prevention in these patients.

Article Abstract

Purpose Of Review: To perform a systematic review and meta-analysis of the prevalence of diabetes in patients with hyperuricemia and gout.

Recent Findings: Previous studies have confirmed that hyperuricemia and gout are associated with an increased risk of diabetes. A previous meta-analysis indicated that the prevalence of diabetes in patients with gout is 16%. Thirty-eight studies (458,256 patients) were included in the meta-analysis. The combined prevalence of diabetes among patients with hyperuricemia and gout were 19.10% (95% confidence interval [CI]: 17.60-20.60; I = 99.40%) and 16.70% (95% CI: 15.10-18.30; I = 99.30%), respectively. Patients from North America showed a higher prevalence of diabetes (hyperuricemia: 20.70% [95% CI: 16.80-24.60], gout: 20.70% [95% CI: 16.80-24.60]) than those from other continents. Older patients with hyperuricemia and those using diuretics showed a higher prevalence of diabetes than younger patients and those who were not using diuretics. Studies with a small sample size, case-control design, and low quality score had a higher prevalence of diabetes than studies with a large sample size, other designs, and a high quality score. The prevalence of diabetes among patients with hyperuricemia and gout is high. Controlling plasma glucose and uric acid levels of patients with hyperuricemia and gout is critical for the prevention of diabetes.

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Source
http://dx.doi.org/10.1007/s11892-023-01506-2DOI Listing

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