Osteonecrosis amid the COVID-19 pandemic.

Rheumatol Int

South Kazakhstan Medical Academy, Shymkent, Kazakhstan.

Published: July 2023

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126548PMC
http://dx.doi.org/10.1007/s00296-023-05332-3DOI Listing

Publication Analysis

Top Keywords

osteonecrosis amid
4
amid covid-19
4
covid-19 pandemic
4
osteonecrosis
1
covid-19
1
pandemic
1

Similar Publications

Background: Osteoclast hyperactivation due to the pathological overproduction of reactive oxygen species (ROS) stimulated by glucocorticoids (GCs) is one of the key drivers behind glucocorticoid-induced osteonecrosis of the femoral head (GIONFH). The insulin degrading enzyme (IDE), a conserved Zn metallo-endopeptidase, facilitates the DNA binding of glucocorticoid receptor and plays a substantial role in steroid hormone-related signaling pathways. However, the potential role of IDE in the pathogenesis of GIONFH is yet undefined.

View Article and Find Full Text PDF

Gambogic amide selectively upregulates TrkA expression and triggers its activation.

Pharmacol Rep

April 2015

Center for Osteonecrosis and Joint Preserving and Reconstruction, Department of Orthopedics, China-Japan Friendship Hospital, Beijing, China. Electronic address:

Background: Gambogic amide is the first identified small molecular agonist for TrkA receptor. It mimics NGF functions by selectively activating TrkA receptor and preventing neuron death. However, its function different from that of NGF remains unknown.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!