Objective: To highlight the current knowledge of the efficacy of dextrose as a prolotherapy agent in managing temporomandibular joint internal derangement (TMJ-ID).
Methods: A "Population, Intervention, Comparison, Outcome" (PICO) strategy was executed using an electronic search through PubMed/MEDLINE, Cochrane databases, and Google Scholar from their inception to August 2022. Only randomized clinical trials investigating the treatment of TMJ-ID with hypertonic dextrose prolotherapy (HDPT) were included. Two independent reviewers assessed the eligibility of the studies with subsequent data extraction.
Results: The systematic search identified 392 studies, and only 8 articles were considered eligible for selection, with a total of 286 patients; 72% were females, and 28% were males. The extracted data showed positive effects of dextrose on joint pain and maximum mouth opening (MMO) with high patient satisfaction.
Conclusion: HDPT can be effective in relieving TMD symptoms as it reduces pain, improves joint dysfunction, and increases MMO up to 12 months.
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| http://dx.doi.org/10.1080/08869634.2023.2204042 | DOI Listing |
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Article Synopsis
- The study explored the effectiveness of dextrose prolotherapy compared to steroid injections in treating distal semimembranous tendinopathy, a rare cause of knee pain.
- It included 25 patients who received either treatment and measured pain and functionality before and after the procedures using VAS and IKDC scores.
- Results showed that while steroid injections provided quicker relief in the first week, dextrose prolotherapy produced better outcomes by the fourth week, indicating both treatments were effective for this condition.*
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