AI Article Synopsis
- Nephrogenic adenoma is a benign growth in the urothelial tract, marked by tubules with thick membranes, but can mimic cancer due to its varied structures.
- Misdiagnosis can occur because it shares features with malignancies like clear cell carcinomas, leading to delayed treatment and worse outcomes.
- The case report highlights a nephrogenic adenoma found in a female urethral diverticulum and emphasizes the need to differentiate it from similar conditions.
Article Abstract
Nephrogenic adenoma is a benign lesion of the urothelial tract characterized by tubules surrounded by thick, hyalinized basement membranes. There is a great variety of architectural patterns within nephrogenic adenomas, including patterns that mimic malignancy, such as focal clear or hobnail cells, areas of significant nuclear atypia, mitosis, and isolated cystic changes. This represents a diagnostic pitfall, where a malignant lesion can be mistaken for a nephrogenic adenoma, leading to a delay in diagnosis and treatment that adversely affects the outcome. In this case report, we describe a nephrogenic adenoma arising in a female urethral diverticulum and discuss the differential diagnosis, which includes clear cell carcinomas, microcystic variant urothelial carcinomas, and Skene's gland cysts.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122436 | PMC |
| http://dx.doi.org/10.7759/cureus.36578 | DOI Listing |
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