AI Article Synopsis

  • Several case reports indicate that patients with IgD multiple myeloma (MM) may successfully stop hemodialysis, although specific predictive factors have not been established.
  • A 57-year-old Japanese woman with renal issues from IgD-λ multiple myeloma underwent bortezomib-based chemotherapy and was able to withdraw from hemodialysis after 50 days.
  • This review suggests that younger age and starting bortezomib-based treatment early could be key indicators for successfully stopping hemodialysis in similar patients.

Article Abstract

Several previous case reports have shown that patients with immunoglobulin D (IgD) multiple myeloma (MM) can be withdrawn from hemodialysis, however, the characteristics that can predict withdrawal in these patients have not yet been elucidated. A 57-year-old Japanese woman required hemodialysis because of renal dysfunction due to IgD-λ and Bence Jones protein-λ MM. Bortezomib-based chemotherapy nine days after admission led to her withdrawal from hemodialysis on Day 50. In our case-based review, younger age and early initiation of bortezomib-based chemotherapy emerged as possible predictors of successful hemodialysis withdrawal.

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http://dx.doi.org/10.18926/AMO/65154DOI Listing

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