Monoclonal antibody: future of malaria control and prevention.

Trans R Soc Trop Med Hyg

Parasite-Host Biology Group, ICMR-National Institute of Malaria Research, Sector 8, Dwarka 110077, New Delhi, India.

Published: September 2023

Monoclonal antibodies (mAbs) are extremely specialized proteins that are cloned from B cells and bind to pathogen epitopes. There are currently no known prophylactic immune-based strategies or efficient, widespread treatments to stop the spread of malaria. In order to lower the prevalence of malaria and its associated mortality, we need mAbs that are capable of offering immediate passive protection against the disease. mAbs have become more crucial in the treatment or prevention of several other infectious diseases. Recently, mAb development for malaria prevention and control has greatly evolved and widespread use in public health settings is now a possibility.

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http://dx.doi.org/10.1093/trstmh/trad027DOI Listing

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