AI Article Synopsis

  • Infection is a major issue for patients with myeloma, leading to significant health problems and fatalities.
  • A new guideline created by experts focuses on preventing infections in myeloma patients by addressing screening for hidden infections, using preventive medications, and recommending vaccinations against key respiratory diseases.
  • This guideline aims to standardize how healthcare providers manage infection risks in myeloma patients, ensuring a comprehensive approach to their care.

Article Abstract

Infection remains a significant contributor to morbidity and mortality in patients with myeloma. This guideline was developed by a multidisciplinary group of clinicians who specialise in the management of patients with myeloma and infection from the medical and scientific advisory group from Myeloma Australia and the National Centre for Infections in Cancer. In addition to summarising the current epidemiology and risk factors for infection in patients with myeloma, this guideline provides recommendations that address three key areas in the prevention of infection: screening for latent infection, use of antimicrobial prophylaxis and immunoglobulin replacement and vaccination against leading respiratory infections (severe acute respiratory syndrome coronavirus 2, influenza and Streptococcus pneumoniae) and other preventable infections. This guideline provides a practical approach to the prevention of infection in patients with myeloma and harmonises the clinical approach to screening for infection, use of prophylaxis and vaccination to prevent infectious complications.

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http://dx.doi.org/10.1111/imj.16100DOI Listing

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