AI Article Synopsis
- Post-polio syndrome (PPS) occurs when previous poliomyelitis survivors experience a return or worsening of motor neuron symptoms decades later.
- It affects 25% to 40% of those who had polio and shows symptoms similar to other motor neuron diseases (MNDs) like amyotrophic lateral sclerosis (ALS).
- The report discusses a 68-year-old man's case of PPS, compares it to ALS, and highlights key differences in their histopathological features.
Article Abstract
Post-polio syndrome (PPS) is characterized by recrudescence or worsening of motor neuron disease symptoms decades after recovery from acute paralytic poliovirus infection, i.e., poliomyelitis. PPS afflicts between 25% and 40% of poliomyelitis survivors and mimics motor neuron diseases (MNDs), such as amyotrophic lateral sclerosis (ALS), due to its selective impairment, degeneration, or death of motor neurons in the brainstem and spinal cord. Herein, we report a case of PPS in a 68-year-old man with a remote history of bulbar and cervical cord involvement by poliomyelitis, review the relevant literature, and contrast the salient histopathologic features that distinguish our case of PPS from ALS.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123742 | PMC |
| http://dx.doi.org/10.3390/neurolint15020035 | DOI Listing |
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