AI Article Synopsis

  • FishGET collects and curates RNA-seq data from various fish studies to improve understanding of gene expression profiles, focusing on new mRNAs and lncRNAs.
  • It has gathered 1362 RNA-seq paired-end data from 8 fish species, utilizing techniques like transcript assembly and functional annotations.
  • A user-friendly web interface has been developed to facilitate research, providing dynamic interactive visualizations of the data.

Article Abstract

With the rapid expansion of transcriptome studies in many fishes, a great number of RNA-seq data have been published, allowing for a more systematic understanding of the general profiles and details of gene expression in fish. FishGET is dedicated to gathering and curating fish RNA-seq data to discover more new RNAs, including mRNA and lncRNA, thereby getting a more complete reference transcriptome and providing more comprehensive and accurate transcriptome annotations. We obtained a total of 1362 RNA-seq paired-end data of 8 fishes from 97 different studies, and then we performed transcript assembly, meta-assembly, weighted gene co-expression network analysis (WGCNA), functional annotations, neighbor location annotation, lncRNA type annotation, homology annotation. To promote research into fish genes at the transcriptional level, we developed a user-friendly web interface that allows users to view all information and makes use of multiple types of dynamic interactive visualization services.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119798PMC
http://dx.doi.org/10.1016/j.isci.2023.106539DOI Listing

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