Objectives: Evaluate the relationship between cardiovascular disease (CVD) risk factors and cochlear function in African Americans.
Methods: Relationships between hearing loss, cochlear function, and CVD risk factors were assessed in a cross-sectional analysis of 1106 Jackson Heart Study participants. Hearing loss was defined as puretone average (PTA) > 15 dB HL. Distortion product otoacoustic emissions (DPOAEs) were collected for = 1.0-8.0 kHz. Two amplitude averages were computed: DPOAE ( ≤ 4 kHz) and DPOAE ( ≥ 6 kHz). Based on major CVD risk factors (diabetes, current smoking, total cholesterol ≥240 mg/dL or treatment, and systolic blood pressure [BP]/diastolic BP ≥ 140/≥90 mmHg or treatment), four risk groups were created: 0, 1, 2, and ≥3 risk factors. Logistic regression estimated the odds of hearing loss and absent/reduced DPOAE and DPOAE by CVD risk status adjusting for age, sex, education, BMI, vertigo, and noise exposure.
Results: With multivariable adjustment, diabetes was associated with hearing loss (OR = 1.48 [95% CI: 1.04-2.10]). However, there was not a statistically significant relationship between CVD risk factors (individually or for overall risk) and DPOAEs.
Conclusion: Diabetes was associated with hearing loss. Neither individual CVD risk factors nor overall risk showed a relationship to cochlear dysfunction.
Level Of Evidence: 2b.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116973 | PMC |
| http://dx.doi.org/10.1002/lio2.1031 | DOI Listing |
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