Trigeminal Trophic Syndrome.

Indian Dermatol Online J

Department of Dermatology, Venereology and Leprology, R.N.T. Medical College, Udaipur, Rajasthan, India.

Published: September 2022

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115313PMC
http://dx.doi.org/10.4103/idoj.idoj_347_21DOI Listing

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Introduction: Destruction of the trigeminal (Gasserian) ganglion or peripheral damage to the trigeminal nerve may lead to trigeminal trophic syndrome (TTS), a rare condition characterized by self-inflicted trauma. To date, under 200 cases of TTS are documented in medical literature, with only sparse studies reporting on oral complications secondary to this condition.

Case Report: The following report presents a well-documented case of oral complications associated with TTS in an 83-year-old Caucasian female presenting with right-sided lesions on her nasal ala, scalp, buccal mucosa, and tongue, secondary to self-inflicted injury following their second microvascular decompression for surgical management of trigeminal neuralgia.

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Article Synopsis
  • - Trigeminal trophic syndrome leads to self-inflicted skin lesions due to nerve damage, while greater auricular trophic syndrome can develop after nerve sacrifice during parotid surgery.
  • - A 59-year-old woman experienced ear ulceration five months post-parotidectomy, diagnosed with greater auricular trophic syndrome and treated effectively with topical clobetasol and behavioral changes.
  • - Unlike other reported cases that involved mental health issues, this case involved a patient without prior psychiatric disorders, demonstrating successful treatment focusing on physical symptoms rather than psychological factors.
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Article Synopsis
  • Trigeminal trophic syndrome (TTS) is a rare condition caused by damage to the trigeminal nerve, leading to facial ulceration, loss of sensation, and abnormal skin sensations, especially near the nostrils.
  • The lesions associated with TTS arise from continuous self-harm and trauma to the affected skin area.
  • This report showcases three individual cases of TTS, emphasizing changes around the eyes and different causes such as strokes and herpes zoster infection.
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Trigeminal Trophic Syndrome With Herpetic Keratitis.

Cornea

October 2024

John F. Hardesty Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO.

Article Synopsis
  • This study reports a unique case of trigeminal trophic syndrome occurring alongside herpetic keratitis in a 42-year-old male with a history of severe facial injuries and nerve damage.
  • The patient was found to have significant facial sensitivity loss and corneal issues linked to herpes, leading to a diagnosis of herpetic keratitis and ulceration due to trigeminal trophic syndrome.
  • Treatment involved antibiotics, antiviral medication, and topical steroids, resulting in improved vision and the use of a custom facial mask to prevent self-harm.
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