Immune mediated colitis: a surgical perspective.

ANZ J Surg

Monash University Department of Surgery, Alfred Hospital, Melbourne, Victoria, Australia.

Published: June 2023

AI Article Synopsis

  • The study reviews current literature on the treatment of immune-mediated colitis and highlights the role of surgical specialties in its management.
  • A narrative review was conducted using various medical databases, focusing on immune-mediated colitis as a side effect of cancer immunotherapy.
  • The findings suggest that while medical specialties traditionally manage this condition, surgeons need to be more involved in the diagnosis and treatment to improve patient outcomes.

Article Abstract

Background: This study aims to review and summarize the current up to date literature that explore the current treatment approaches to immune mediated colitis and the role of surgical specialties in the landscape of management.

Methods: A narrative review of papers was performed following a literature search through Medline, EMBASE and Cochrane Central databases pertaining to immune mediated colitis as an adverse event of cancer immunotherapy.

Results: Current guidelines for the diagnosis and treatment of immune mediated colitis mirror the approach to the workup of inflammatory bowel disease and guided by treating oncology and gastroenterology specialties. Immune mediated colitis however relies on surgical specific skills as a consequence of obtaining a diagnosis as well as in the management of complications that may arise.

Conclusion: Immune mediate colitis management has largely been under the purview of medical specialties. This review explores the current landscape of managing immune mediated colitis from a surgical perspective and highlights key areas in which surgeons can engage in the multidisciplinary care of this condition. To facilitate prompt diagnosis and management of immune-mediated colitis, there is an increasing necessity for surgeons to become familiar with the latest multidisciplinary approaches and recommendations.

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Source
http://dx.doi.org/10.1111/ans.18485DOI Listing

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