The Royal's Institute of Mental Health Research, 1145, Carling Avenue, Ottawa, ON, K1Z 7K4, Canada; Department of Psychiatry, University of Ottawa, 1145, Carling Avenue, Ottawa, ON, K1Z 7K4, Canada; Department of Cellular and Molecular Medicine, University of Ottawa, 451, Smyth Road, Ottawa, ON, K1H 8M5, Canada.