The sensitive and selective nicotine detection in cigarette is necessary due to the cigarette addiction problem and the neurotoxicity of nicotine on human body. In this study, a novel electrochemiluminescence (ECL) emitter with excellent performance was prepared for nicotine analysis, by combining Zr-based metal organic framework (Zr-MOF) and branched polyethylenimine (BPEI)-coated Ru(dcbpy) through electrostatic interaction. Ru(dcbpy) integrated by Zr-MOF could be catalyzed by the reaction intermediates SO, produced from the co-reactant SO, resulting in a significant increase in ECL response. Interestingly, SO with strong oxidizing ability could preferentially oxidize nicotine, leading to ECL quenching. The constructed ECL sensor based on the Ru-BPEI@Zr-MOF/SO system displayed ultrasensitive determination of nicotine with a lower detection limit of 1.9 × 10 M (S/N = 3), which is three orders lower than previously reported ECL results and 4-5 orders lower than that of other types of method. This method puts forward a new approach for building efficient ECL system with greatly improved ECL sensitivity for nicotine detection.
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| http://dx.doi.org/10.1016/j.talanta.2023.124539 | DOI Listing |
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