A collection of thin structures buckle, bend, and bump into each other when confined. This contact can lead to the formation of patterns: hair will self-organize in curls; DNA strands will layer into cell nuclei; paper, when crumpled, will fold in on itself, forming a maze of interleaved sheets. This pattern formation changes how densely the structures can pack, as well as the mechanical properties of the system. How and when these patterns form, as well as the force required to pack these structures is not currently understood. Here we study the emergence of order in a canonical example of packing in slender structures, i.e., a system of parallel confined elastic beams. Using tabletop experiments, simulations, and standard theory from statistical mechanics, we predict the amount of confinement (growth or compression) of the beams that will guarantee a global system order, which depends only on the initial geometry of the system. Furthermore, we find that the compressive stiffness and stored bending energy of this metamaterial are directly proportional to the number of beams that are geometrically frustrated at any given point. We expect these results to elucidate the mechanisms leading to pattern formation in these kinds of systems and to provide a new mechanical metamaterial, with a tunable resistance to compressive force.
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http://dx.doi.org/10.1103/PhysRevLett.130.148201 | DOI Listing |
CBE Life Sci Educ
March 2025
Department of Psychology, Northeastern University, Boston, MA, 02115.
Previous research has shown that students employ intuitive thinking when understanding scientific concepts. Three types of intuitive thinking-essentialist, teleological, and anthropic thinking-are used in biology learning and can lead to misconceptions. However, it is unknown how commonly these types of intuitive thinking, or cognitive construals, are used spontaneously in students' explanations across biological concepts and whether this usage is related to endorsement of construal-consistent misconceptions.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6.
Although chromatin remodelers are among the most important risk genes associated with neurodevelopmental disorders (NDDs), the roles of these complexes during brain development are in many cases unclear. Here, we focused on the recently discovered ChAHP chromatin remodeling complex. The zinc finger and homeodomain transcription factor ADNP is a core subunit of this complex, and de novo mutations lead to intellectual disability and autism spectrum disorder.
View Article and Find Full Text PDFPLoS One
January 2025
Departament de Ciències Matemàtiques i Informàtica, Universitat de les Illes Balears, Palma, Spain.
Here we introduce CBGTPy, a virtual environment for designing and testing goal-directed agents with internal dynamics that are modeled on the cortico-basal-ganglia-thalamic (CBGT) pathways in the mammalian brain. CBGTPy enables researchers to investigate the internal dynamics of the CBGT system during a variety of tasks, allowing for the formation of testable predictions about animal behavior and neural activity. The framework has been designed around the principle of flexibility, such that many experimental parameters in a decision making paradigm can be easily defined and modified.
View Article and Find Full Text PDFPLoS One
January 2025
South African Grape and Wine Research Institute, Stellenbosch University, Stellenbosch, South Africa.
Hyphopichia pseudoburtonii, is emerging as a potential biocontrol agent against various phytopathogens. These traits have been attributed to the production of various antifungal compounds in the presence of target pathogens. However, the broad molecular mechanisms involved in the antifungal activity are not yet understood.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Forestry, University of Gondar, Gondar, Ethiopia.
Owing to its topographic variations, Ethiopia is a biodiversity-rich country. However, the long-term degradation of resources has resulted in isolated forest patches largely around sacred places. Thus, this work was aimed to evaluate the plant community formation and structural dynamics of the Abraham Sacred Forest patch.
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