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| http://dx.doi.org/10.1007/s00401-023-02573-1 | DOI Listing |
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Systemic Glucose Homeostasis Requires Pancreatic but Not Neuronal ATP-Sensitive Potassium Channels.
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Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.
The ATP-sensitive potassium (KATP) channels, composed of Kir6.2 and SUR1 subunits, are essential for glucose homeostasis. While the role of pancreatic KATP channels in regulating insulin secretion is well-documented, the specific contributions of neuronal KATP channels remain unclear due to challenges in precisely targeting neuronal subpopulations.
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