Protocol for quantitative characterization of human retinotopic maps using quasiconformal mapping.

STAR Protoc

School of Computing and Augmented Intelligence, Arizona State University, Tempe, AZ, USA. Electronic address:

Published: April 2023

High-field functional magnetic resonance imaging generates in vivo retinotopic maps, but quantifying them remains challenging. Here, we present a pipeline based on conformal geometry and Teichmüller theory for the quantitative characterization of human retinotopic maps. We describe steps for cortical surface parameterization and surface-spline-based smoothing. We then detail Beltrami coefficient-based mapping, which provides a quantitative and re-constructible description of the retinotopic maps. This framework has been successfully used to analyze the Human Connectome Project's V1 retinotopic maps. For complete details on the use and execution of this protocol, please refer to Ta et al. (2022)..

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323127PMC
http://dx.doi.org/10.1016/j.xpro.2023.102246DOI Listing

Publication Analysis

Top Keywords

retinotopic maps
20
quantitative characterization
8
characterization human
8
human retinotopic
8
retinotopic
5
maps
5
protocol quantitative
4
maps quasiconformal
4
quasiconformal mapping
4
mapping high-field
4

Similar Publications

Computational theories posit that attention is guided by a combination of spatial maps for individual features that can be dynamically weighted according to task goals. Consistent with this framework, when a stimulus contains several features, attending to one or another feature results in stronger fMRI responses in regions preferring the attended feature. We hypothesized that multivariate activation patterns across feature-responsive cortical regions form spatial 'feature dimension maps', which combine to guide attentional priority.

View Article and Find Full Text PDF

Adaptive behavior in complex environments requires integrating visual perception with memory of our spatial environment. Recent work has implicated three brain areas in posterior cerebral cortex - the place memory areas (PMAs) that are anterior to the three visual scene perception areas (SPAs) - in this function. However, PMAs' relationship to the broader cortical hierarchy remains unclear due to limited group-level characterization.

View Article and Find Full Text PDF

Mid-level visual processing represents a crucial stage between basic sensory input and higher-level object recognition. The conventional model posits that fundamental visual qualities like color and motion are processed in specialized, retinotopic brain regions (e.g.

View Article and Find Full Text PDF

EphA4 Mediates EphrinB1-Dependent Adhesion in Retinal Ganglion Cells.

J Neurosci

January 2025

Instituto de Neurociencias de Alicante (Consejo Superior de Investigaciones Científicas-Universidad Miguel Hernández, CSIC-UMH), Campus San Juan, Alicante 03550, Spain

Eph/ephrin signaling is crucial for organizing retinotopic maps in vertebrates. Unlike other EphAs, which are expressed in the embryonic ventral retina, EphA4 is found in the retinal ganglion cell (RGC) layer at perinatal stages, and its role in mammalian visual system development remains unclear. Using classic in vitro stripe assays, we demonstrate that, while RGC axons are repelled by ephrinB2, they grow on ephrinB1 stripes through EphA4-mediated adhesion.

View Article and Find Full Text PDF

ENHANCING 3T RETINOTOPIC MAPS USING DIFFEOMORPHIC REGISTRATION.

Proc IEEE Int Symp Biomed Imaging

May 2024

School of Computing, Informatics, and Decision Systems Engineering, Arizona State University, Tempe, AZ, USA.

Retinotopic mapping aims to uncover the relationship between visual stimuli on the retina and neural responses on the visual cortical surface. This study advances retinotopic mapping by applying diffeomorphic registration to the 3T NYU retinotopy dataset, encompassing analyze-PRF and mrVista data. Diffeomorphic Registration for Retinotopic Maps (DRRM) quantifies the diffeomorphic condition, ensuring accurate alignment of retinotopic maps without topological violations.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!