A concise and efficient method has been developed herein for the synthesis of valuable naphtho[1,2-d]imidazole derivatives. It involves an earth-abundant cobalt-catalyzed electrophilic C-H amination/cyclization/directing group removal cascade with -benzoloxyamines using paraformaldehyde as a one carbon synthon. Picolinamide has been utilized as a traceless directing group. A boosting effect of HFIP is found in the whole process. The reaction conditions are very simple and allow easy handling, making this methodology valuable and appealing.
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