A Positive Microbubble Study in Ventricular Septal Defect Patient Without Pulmonary Hypertension.

JACC Case Rep

The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China.

Published: April 2023

A stroke patient with supracristal ventricular septal defect accompanying suspected patent foramen ovale underwent transthoracic and transesophageal echocardiography with agitated saline microbubble study, a positive trans-ventricular microbubble jet after Valsalva maneuver provocation was detected, indicating instantaneous transient paradoxical right-to-left shunt at late diastole might be the etiology of embolic events. ().

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107004PMC
http://dx.doi.org/10.1016/j.jaccas.2023.101782DOI Listing

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