Unbalanced global vaccine product trade pattern: A network perspective.

Soc Sci Med

Institute for Global Innovation & Development, East China Normal University, Shanghai, 200062, China; School of Urban and Regional Science, East China Normal University, Shanghai, 200062, China. Electronic address:

Published: May 2023

Mass vaccination is the most cost-effective intervention in response to public health events. Thus, equitable access to vaccine products is essential to ensure global human health. Based on the global vaccine product trade data from 2000 to 2018 and employing social network analysis, this paper explores the unbalanced pattern of global vaccine product trade and assesses the sensitivity interdependence between countries. Overall, the analysis shows that global vaccine product trade links have long been highly concentrated within developed countries in Europe and America. Nevertheless, with the rise of global and regional hub countries, the global vaccine product trade network has begun to evolve from a unipolar structure with the U.S. as the sole core to a multipolar structure with the U.S. and Western European countries as the core. Meanwhile, emerging countries, represented by China and India, are increasingly participating in the global vaccine product trade network and are beginning to play an important role. The formation of this multipolar pattern has provided countries in the Global South with more options for cooperation in the vaccine product trade and reduces the sensitivity interdependence of network periphery countries on core countries, which consequently reduces the global supply risk of vaccine products.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.socscimed.2023.115913DOI Listing

Publication Analysis

Top Keywords

vaccine product
28
product trade
28
global vaccine
24
vaccine
9
global
9
vaccine products
8
sensitivity interdependence
8
countries
8
countries global
8
trade network
8

Similar Publications

Rapid urbanization and migration in Latin America have intensified exposure to insect-borne diseases. Malaria, Chagas disease, yellow fever, and leishmaniasis have historically afflicted the region, while dengue, chikungunya, and Zika have been described and expanded more recently. The increased presence of synanthropic vector species and spread into previously unaffected areas due to urbanization and climate warming have intensified pathogen transmission risks.

View Article and Find Full Text PDF

Interplay of swine acute diarrhoea syndrome coronavirus and the host intrinsic and innate immunity.

Vet Res

January 2025

Department of Preventive Veterinary Medicine, Research Center for Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130, China.

Swine acute diarrhoea syndrome coronavirus (SADS-CoV), a novel HKU2-related coronavirus of bat origin, is a newly emerged swine enteropathogenic coronavirus that causes severe diarrhoea in piglets. SADS-CoV has a broad cell tropism with the capability to infect a wide variety of cells from human and diverse animals, which implicates its ability to hold high risks of cross-species transmission. The intracellular antiviral immunity, comprised of the intrinsic and innate immunity, represents the first line of host defence against viral infection prior to the onset of adaptive immunity.

View Article and Find Full Text PDF

Background: The COVID-19 pandemic has highlighted the need for more effective immunization programs, including in limited resource settings. This paper presents outcomes and lessons learnt from a COVID-19 vaccination campaign (VC), which used a tailored adaptive strategy to optimise vaccine uptake in the Boeny region of Madagascar.

Methods: Guided by the Dynamic Sustainability Framework (DSF), the VC implementation was regularly reviewed through multi-sectoral stakeholder feedback, key informant interviews, problem-solving meetings, and weekly monitoring of outcome indicators to identify and apply key adaptations.

View Article and Find Full Text PDF

Background: Hepatitis B virus (HBV) surface antigen (HBsAg) seroprevalence was high before the national vaccine policy was introduced in Taiwan, indicating significant HBV infection rates. The success of the HBV immunization program and other preventive measures likely led to decreased HBsAg prevalence among pregnant women. This study reports on the HBV seroprevalence among pregnant women in Taiwan from 2016 to 2021, including those potentially affected by the universal hepatitis B vaccination at birth.

View Article and Find Full Text PDF

Engineering Saccharomyces cerevisiae for medical applications.

Microb Cell Fact

January 2025

Chair of Biochemistry of Microorganisms, Faculty of Life Sciences: Food, Nutrition and Health, University of Bayreuth, 95326, Kulmbach, Germany.

Background: During the last decades, the advancements in synthetic biology opened the doors for a profusion of cost-effective, fast, and ecologically friendly medical applications priorly unimaginable. Following the trend, the genetic engineering of the baker's yeast, Saccharomyces cerevisiae, propelled its status from an instrumental ally in the food industry to a therapy and prophylaxis aid.

Main Text: In this review, we scrutinize the main applications of engineered S.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!