AI Article Synopsis
- The study investigates the effects of COVID-19 on heart health in ICU patients on mechanical ventilation, measuring heart rate variability (HRV) as an indicator of cardiac autonomic control.
- It involved 82 subjects, comparing COVID-19 positive (COVID(+)) and negative (COVID(-)) groups, revealing that both had lower HRV than normal, with the COVID(+) group showing increased low frequency and decreased high frequency HRV components.
- The findings suggest that reduced HRV, especially in COVID(+) patients, may indicate a higher risk of cardiac complications, underscoring the need for careful monitoring in these patients.
Article Abstract
Background: Coronavirus disease 2019 (COVID-19) can damage cardiac tissue by increasing troponin levels and inducing arrhythmias, myocarditis, and acute coronary syndrome.
Objectives: To analyze the impact of COVID-19 on cardiac autonomic control in mechanically ventilated intensive care unit (ICU) patients.
Design And Setting: This cross-sectional analytical study of ICU patients of both sexes receiving mechanical ventilation was conducted in a tertiary hospital.
Methods: Patients were divided into COVID-19-positive (COVID(+)) and COVID-19-negative (COVID(-)) groups. Clinical data were collected and heart rate variability (HRV) records obtained using a heart rate monitor.
Results: The study sample comprised 82 subjects: 36 (44%) in the COVID(-) group (58.3% female; median age, 64.5 years) and 46 (56%) in the COVID(+) group (39.1% females; median age, 57.5 years). The HRV indices were lower than the reference values. An intergroup comparison identified no statistically significant differences in the mean normal-to-normal (NN) interval, standard deviation of the NN interval, or root mean square of successive differences in NN intervals. The COVID(+) group had an increased low frequency (P = 0.05), reduced high frequency (P = 0.045), and increased low frequency/high frequency (LF/HF) ratio (P = 0.048). There was a weak positive correlation between LF/HF and length of stay in the COVID(+) group.
Conclusion: Patients who received mechanical ventilation had lower overall HRV indices. COVID(+) patients who received mechanical ventilation had lower vagal HRV components. These findings likely indicate clinical applicability, as autonomic control impairments are associated with a greater risk of cardiac death.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109544 | PMC |
| http://dx.doi.org/10.1590/1516-3180.2022.0513.R1.09022023 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mechanical power and VILI: modeling limits and unknowns.
Intensive Care Med Exp
January 2025
Department of Pulmonary and Critical Care Medicine, University of Minnesota, St Paul, Minneapolis, MN, USA.
[Beyond premature apnea pauses: congenital myotonic dystrophy type 1].
Andes Pediatr
October 2024
Departamento de Neuropediatría, Hospital Fundación Alcorcón, Madrid, España.
Unlabelled: Congenital myotonic dystrophy type 1 (DM1) is a rare entity that can pose a diagnostic challenge, especially if other processes such as prematurity coexist.
Objective: to describe the typical presentation of congenital DM1 and thus increase diagnostic suspicion.
Clinical Case: A 29-week preterm female newborn who required non-invasive mechanical ventilation until 41 weeks postmenstrual age; she presented with apnea requiring manual ventilation with a self-inflating bag and cardiac massage.
[Factors associated with breastfeeding one month after discharge in very low weight premature infants hospitalized at birth].
Andes Pediatr
October 2024
Instituto de Enfermería, Facultad de Medicina, Universidad Austral de Chile, Valdivia, Chile.
Unlabelled: There is evidence of the benefits that breastfeeding (BF) provides to full-term and premature newborns who are hospitalized. In the latter, maintaining BF during and after hospitalization is difficult.
Objective: To determine the factors associated with BF cessation in preterm infants one month after discharge from a neonatology unit.
[Can CPAP prevent the progression of pediatric acute respiratory distress syndrome? A decade of experience in a Reference Center].
Andes Pediatr
October 2024
Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago, Chile.
Viral infections are the main cause of acute respiratory failure in infants, which can progress to acute respiratory distress syndrome (ARDS), with high morbidity and mortality, so it is essential to imple ment strategies that prevent this progression. Recently, it has been proposed that increased work of breathing would not only be a warning symptom during the evolution of acute respiratory failure, but also a mechanism for the progression of injury, both lungs and diaphragm, coining the concept of patient self-inflicted lung injury. Since the first reports of ARDS, the usefulness of the use of con tinuous positive airway pressure (CPAP) has been raised, a non-invasive respiratory support therapy with wide access and low cost, capable of improving oxygenation and work of breathing.
View Article and Find Full Text PDF[High flow nasal cannula: is it a risk factor of bronchopulmonary dysplasia and retinopathy of premature?].
Andes Pediatr
August 2024
Servicio de Neonatologia, Complejo Asistencial Dr. Sótero del Río, Santiago, Chile.
Unlabelled: Observational studies have described an increase in the duration of oxygen therapy, bronchopulmonary dysplasia (BPD), and retinopathy of prematurity (ROP) in relation to the use of high-flow nasal cannula (HFNC, 2013-2016).
Objective: to analyze changes in the evolution of very preterm newborns with the use of HFNC.
Patients And Method: The incidence of neonatal pathologies between 2013 and 2021 was analyzed with a statistical process control.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!