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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109343 | PMC |
| http://dx.doi.org/10.1590/0037-8682-0107-2023 | DOI Listing |
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Long term health outcomes in people with diabetes 12 months after hospitalisation with COVID-19 in the UK: a prospective cohort study.
EClinicalMedicine
January 2025
Leicester Real World Evidence Unit, Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, LE5 4PW, UK.
Background: People with diabetes are at increased risk of hospitalisation, morbidity, and mortality following SARS-CoV-2 infection. Long-term outcomes for people with diabetes previously hospitalised with COVID-19 are, however, unknown. This study aimed to determine the longer-term physical and mental health effects of COVID-19 in people with and without diabetes.
View Article and Find Full Text PDFCohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study.
Int J Epidemiol
February 2024
The Institute for Lung Health, NIHR Leicester Biomedical Research Centre-Respiratory, University of Leicester, Leicester, UK.
Discovery of Arylpiperazines with Broad-Spectrum Antimicrobial Activity and Favorable Pharmacokinetic Profiles.
Chem Biodivers
September 2024
Laboratório de Síntese de Candidatos a Fármacos (LaSFar), Institute of Chemistry, Federal University of Uberlândia, Uberlândia-MG, 38400-902, Brazil.
Microorganisms can induce diseases with significant clinical implications for human health. Multidrug-resistant microorganisms have been on the rise worldwide over the past few decades, and no new antibiotics have been introduced to the market in a considerable amount of time. Such situation highlights the urgency of discovering new antimicrobial drugs to address this pressing issue.
View Article and Find Full Text PDFCognitive and psychiatric symptom trajectories 2-3 years after hospital admission for COVID-19: a longitudinal, prospective cohort study in the UK.
Lancet Psychiatry
September 2024
Department of Psychiatry, University of Oxford, Oxford, UK; Oxford Health NHS Foundation Trust, Oxford, UK; NIHR Oxford Health Biomedical Research Centre, Oxford, UK.
Background: COVID-19 is known to be associated with increased risks of cognitive and psychiatric outcomes after the acute phase of disease. We aimed to assess whether these symptoms can emerge or persist more than 1 year after hospitalisation for COVID-19, to identify which early aspects of COVID-19 illness predict longer-term symptoms, and to establish how these symptoms relate to occupational functioning.
Methods: The Post-hospitalisation COVID-19 study (PHOSP-COVID) is a prospective, longitudinal cohort study of adults (aged ≥18 years) who were hospitalised with a clinical diagnosis of COVID-19 at participating National Health Service hospitals across the UK.
Article Synopsis
- The study aimed to create a new prognostic model to estimate the risk of pulmonary complications after elective surgery, which is the leading cause of post-surgery death.
- Data from a large international cohort of over 86,000 patients was used, applying machine learning techniques to identify risk factors for complications like pneumonia and respiratory distress.
- The model, named the GSU-Pulmonary Score, was validated with additional cohorts and is available as an online tool to assist in patient care and resource management, especially important during pandemic recovery.
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