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Periorbital Orange Spots.
Cutis
February 2023
Virginia Commonwealth University School of Medicine, Richmond. Dr. Venna also is from the Inova Schar Melanoma and Skin Cancer Center, Fairfax, Virginia.
Anatomic and Functional Imaging of Immunoglobulin G4-related Disease and Its Mimics.
Radiographics
March 2023
From the Department of Radiological Sciences, University of California-Irvine, Orange, Calif (K.N.H.); and Department of Radiology, Mayo Clinic Scottsdale, 13400 E Shea Blvd, Scottsdale, AZ 85259 (M.J.K., B.D.N.).
Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) is an immune-mediated fibrosclerosing disease with tumefactive lesions infiltrated by IgG4-positive plasma cells. Initially described as autoimmune pancreatitis, IgG4-RD is now recognized as a discrete entity and is found to affect virtually any organ in the body. Common extrapancreatic sites include the biliary tree, salivary glands, periorbital tissue, lungs, kidneys, lymph nodes, aorta, retroperitoneum, and thyroid gland.
View Article and Find Full Text PDFClinical Evidence of Effects of Green Mandarin (Putgyul) Extract on Skin Aging: A Randomized, Double Blind, Placebo-Controlled Study.
Nutrients
March 2022
Biodiversity Research Institute, Jeju Technopark, Jeju 63608, Korea.
Green mandarins are widely consumed unripe as mandarin oranges (), which exhibit anti-inflammatory and anti-wrinkle effects by inhibiting the production of inflammatory cytokines and matrix metalloproteinase. A randomized, double-blind, placebo-controlled clinical study was performed to verify the skin improvement efficacy and safety of green mandarin extract (PTE). For the standardization of PTE, narirutin was set as a marker compound, and PTE with a constant narirutin content was prepared for the study.
View Article and Find Full Text PDFFavre-Racouchot disease: protective effect of solar elastosis.
Arch Dermatol Res
April 2022
Dermatology, Rutgers New Jersey Medical School, 185 South Orange Ave, Newark, NJ, 07103, USA.
Favre-Racouchot disease (FRD) is an occupational disorder characterized by solar elastosis with open and cystically dilated comedones that tend to appear on the periorbital and temporal face of elderly light-complexioned men. It is a benign condition caused by chronic excessive ultraviolet exposure, as well as ionizing radiation and/or smoking. However, malignant skin neoplasms are uncommonly observed arising in FRD, which suggests a protective role of some element of FRD against carcinogenesis.
View Article and Find Full Text PDFA Multicenter Cross-Sectional Study and Systematic Review of Necrobiotic Xanthogranuloma With Proposed Diagnostic Criteria.
JAMA Dermatol
March 2020
Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Importance: Necrobiotic xanthogranuloma (NXG) is a non-Langerhans cell histiocytosis classically associated with paraproteinemia attributable to plasma-cell dyscrasias or lymphoproliferative disorders. Despite the morbidity of NXG, the literature is limited to case reports and small studies, and diagnostic criteria are lacking.
Objective: To evaluate the characteristics of NXG and propose diagnostic criteria.
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