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Article Synopsis
  • * A study analyzed data from 395 patients (2009-2018) to compare long-term clinical outcomes of those with AKD versus those without, focusing on major adverse kidney and cardiovascular events.
  • * Findings showed that patients with AKD had double the risk of major kidney events and increased cardiovascular risks in the first three years post-ECMO, along with higher rates of hospital readmissions for various reasons.
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Aim: To ascertain the association between body composition, including muscle mass and adiposity, and patient mortality in those requiring extracorporeal membrane oxygenation (ECMO) for acute respiratory failure.

Materials And Methods: A retrospective study was undertaken of all patients with acute respiratory failure requiring veno-venous (VV) ECMO between January 2015 and December 2019. Automated image segmentation software was used to quantify the cross-sectional area and average radiodensity (in Hounsfield units) of different muscle and fat compartments at the L3 level of whole-body computed tomography (CT) images taken within 48 h of initiation of ECMO support.

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Objectives: To investigate changes in von Willebrand factor (VWF) concentration, function, and multimers during pediatric extracorporeal membrane oxygenation (ECMO) and determine whether routine monitoring of VWF during ECMO would be useful in predicting bleeding.

Design: Prospective observational study of pediatric ECMO patients from April 2017 to May 2019.

Setting: The PICU in a large, tertiary referral pediatric ECMO center.

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In-hospital and 6-month outcomes in patients with COVID-19 supported with extracorporeal membrane oxygenation (EuroECMO-COVID): a multicentre, prospective observational study.

Lancet Respir Med

February 2023

2nd Department of Internal Medicine, Cardiovascular Medicine General Teaching Hospital, Prague, Czech Republic; 1st Faculty of Medicine, Charles University, Prague, Czech Republic.

Article Synopsis
  • The study investigates in-hospital mortality and post-discharge outcomes for patients with COVID-19 who received ECMO during the pandemic's first wave (March 1 - Sept 13, 2020).
  • Conducted by the European Extracorporeal Life Support Organization, it included 1215 patients from 21 countries and focused on various patient-related factors affecting survival rates.
  • Findings revealed a 50% in-hospital mortality rate, with factors like age, pre-ECMO complications, and delays in ECMO initiation linked to higher mortality.
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