Aims: Indirect pulp-capping treatment is a procedure applied to teeth with deep and close-to-pulp caries lesions and without pulp degeneration symptoms. This study aimed to explore the use of a material containing bioactive glass for indirect pulp capping in primary and permanent teeth.
Materials And Methods: The study included 145 patients, aged 4-15 years, without any systemic disease and 100 primary second molars and 100 permanent first molars in total. Four material groups were determined: calcium hydroxide (Dycal-DC group), glass ionomer (Biner LC-BC group), calcium silicate (TheraCal LC-TC group), and Bioactive glass-containing ACTIVA BioACTIVE-AC group. Clinical and radiographic evaluations were made 1, 3, 6, 9, and 12 months after the treatment. The data obtained were statistically analyzed using the Chi-square test.
Results: During the 12-month follow-up period, the DC and TC groups were more successful clinically (94%), while the DC and AC groups were found to be more successful radiographically (94%). However, no statistically significant difference was found between the groups ( > 0.05).
Conclusions: The results of this study supported the view that the success of indirect pulp-capping treatments was independent of the material used.
Clinical Significance: This study demonstrated that a material containing bioactive glass, ACTIVA BioACTIVE-Base/Liner, can be used safely in indirect pulp-capping processes.
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http://dx.doi.org/10.5005/jp-journals-10024-3428 | DOI Listing |
J Dent Sci
January 2025
Department of Fragrance and Cosmetic Science, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan.
Background/purpose: Various pulp-covering materials offer advantages in regenerative root canal treatment, but each has limitations, highlighting the need for more effective antibacterial strategies for pulp repair and regeneration. Mesoporous bioactive glasses (MBG) show significant biological activity, making them valuable in tissue/dental repair. Silver-incorporated MBG exhibits promising antibacterial effects against various bacteria; copper ions are crucial in regulating angiogenesis signals.
View Article and Find Full Text PDFNanoscale
January 2025
Analytical & Testing Center; West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu 610064, China.
Continuous microenvironment modulation is an ongoing challenge in wound dressing, which includes excessive exudate absorption, oxygen delivery, bacterial inhibition and angiogenesis. Herein, we developed an construction strategy to fabricate a self-retaining double-layered wound dressing, where the top layer precursor was composed of Ca-containing polyvinyl butyral (PVB) solution dispersed with hydroxypropyl methylcellulose (HPMC) particles, and the bottom one consisted of sodium alginate (Alg) solution blended with Ag-doped mesoporous bioactive glass powders (Ag-MBG). When in use, both precursors were simultaneously squeezed out from the twin nozzles connected to the individual chambers of a twin-chambered syringe, whereby Ca in the top layer rapidly migrated downwards to crosslink Alg in the bottom layer, leading to the formation of an Alg/Ag-MBG (AA) functional hydrogel for filling an irregular wound.
View Article and Find Full Text PDFJ Int Soc Prev Community Dent
December 2024
Department of Pediatric Dentistry, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
Aims: This study aimed to evaluate the enamel remineralization effect of fluoride-incorporated bioactive glass (F-BG) toothpaste on artificial subsurface caries in primary teeth.
Materials And Methods: Forty sound primary maxillary incisors were subjected to a demineralizing solution for four days to induce artificial enamel caries. The teeth were randomly divided into four experimental groups ( = 10 per group): Group I, F-BG toothpaste (530 ppm fluoride) (BiominF); Group II, 0.
J Int Soc Prev Community Dent
December 2024
Department of Environmental Science, School of Life Sciences, Mysuru, JSS Academy of Higher Education and Research, Mysore, Karnataka, India.
Background: Importance of fluoride in dental restorative materials for preventing secondary caries. Several commercially available tooth-colored dental restorative materials, such as glass ionomer cement, resin composites, and compomers were used for this study.
Aim: To evaluate the amount of fluoride release from tooth-colored restorative materials [Conventional Glass Ionomer Cement (GC Fuji II)], Resin-modified Glass Ionomer Cement (ACTIVA BioACTIVE-RESTORATIVE), and Giomer (BEAUTIFIL II LS)] using ion-selective electrode (ISE) and spectrophotometer using zirconyl alizarin red dye method.
Biotechnol J
January 2025
Cancer Hospital of Dalian University of Technology, Dalian R&D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, China.
Osteochondral damage, caused by trauma, tumors, or degenerative diseases, presents a major challenge due to the limited self-repair capacity of the tissue. Traditional treatments often result in significant trauma and unpredictable outcomes. Recent advances in bone/cartilage tissue engineering, particularly in scaffold materials and fabrication technologies, offer promising solutions for osteochondral regeneration.
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