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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111832PMC
http://dx.doi.org/10.1186/s12906-023-03958-1DOI Listing

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Article Synopsis
  • Diabetic nephropathy (DN) is a significant complication of diabetes, and Qingxin Lianzi Yin Decoction (QXLZY) shows promise as a treatment, though its molecular mechanisms remain unclear.* -
  • This study developed methods to determine the content of key components in QXLZY and used network pharmacology and metabolomics to investigate its effects on DN.* -
  • Results indicated that QXLZY treatment improved kidney health in diabetic mice, reversed metabolic disturbances, and influenced essential metabolic pathways, suggesting its potential as an effective therapy for DN.*
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Corrigendum: SbWRKY75- and SbWRKY41- mediated jasmonic acid signaling regulates baicalin biosynthesis.

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The State Administration of Traditional Chinese Medicine (SATCM) Key Laboratory for New Resources & Quality Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

[This corrects the article DOI: 10.3389/fpls.2023.

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This study aimed to investigate the angelica sinensis - radix rehmanniae (AR) role in polycystic ovary syndrome (PCOS), employing network pharmacology and molecular docking techniques for active ingredient, targets, and pathway prediction. AR active components were obtained through TCMSP platform and literature search. The related targets of AR and PCOS were obtained through the disease and Swiss Target Prediction databases.

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Acute myocardial infarction remains the leading cause of death in humans. Timely restoration of blood perfusion to ischemic myocardium remains the most effective strategy in the treatment of acute myocardial infarction, which can significantly reduce morbidity and mortality. However, after restoration of blood flow and reperfusion, myocardial injury will aggravate and induce apoptosis of cardiomyocytes, a process called myocardial ischemia-reperfusion injury.

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