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Modern surgical treatments for lymphedema.
Scand J Surg
December 2024
Department of Plastic and Maxillofacial Surgery, Uppsala University Hospital, Uppsala, Sweden.
Lymphedema occurs when the lymphatic system is malformed, leaking or is damaged by infection or cancer treatment. Enlarged extremities due to extensive fluid retention and adipose tissue deposition, recurrent cellulitis, and the requirement for hard-to-wear compression garments lead to impaired limb function and decreased quality of life. This narrative review aims to elucidate classification, diagnostic tools, and conservative management strategies leading the path to patient selection for microsurgical reconstructive procedures or volume reduction procedures.
View Article and Find Full Text PDFLymphovenous anastomosis and complex decongestive therapy for severe deformed lymphedema with recurrent infection: A case report.
World J Clin Cases
August 2024
Department of Oncology, The 960 Hospital of People's Liberation Army, Jinan 250000, Shandong Province, China.
Article Synopsis
- Lower extremity lymphedema is a frequent complication in patients treated for gynecological cancers, affecting up to 70% of them and currently lacking standardized treatment protocols.
- A case study details a 40-year-old woman who developed severe bilateral leg swelling and complications six years post-endometrial cancer treatment, ultimately leading to significant functional impairment.
- Following a combination of complex decongestive therapy and lymphaticovenous anastomosis, she experienced marked improvements, including substantial weight loss, reduced swelling, eliminated pain, and restored mobility.
First case report of intestinal lymphangiectasia with refractory bleeding from the duodenum, successfully treated by intra-abdominal lymphaticovenous anastomosis with venous ligation.
Clin J Gastroenterol
October 2024
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Article Synopsis
- Intestinal lymphangiectasia (IL) is a condition that causes a loss of protein from the digestive system, which can sometimes lead to gastrointestinal bleeding.
- A 41-year-old woman with a long history of this condition experienced worsening symptoms despite various treatments and became dependent on blood transfusions.
- After undergoing a surgical procedure to address the leakage of lymph fluid into her digestive tract, she saw significant improvement and remained symptom-free for over six months.
Isolated Conjunctival Lymphaticovenous Malformation Presenting as Persistent Conjunctival Chemosis.
Klin Monbl Augenheilkd
January 2024
Department of Ophthalmology, LMU University Hospital, LMU Munich, Germany.
Pathophysiology of Slow-Flow Vascular Malformations: Current Understanding and Unanswered Questions.
J Vasc Anom (Phila)
September 2023
Department of Obstetrics and Gynecology, Department of Surgery, Columbia University Irving Medical Center, New York, NY.
Background: Slow-flow vascular malformations include venous, lymphatic, and lymphaticovenous malformations. Recent studies have linked genetic variants hyperactivating either the PI3K/AKT/mTOR and/or RAS/RAF/MAPK signaling pathways with slow-flow vascular malformation development, leading to the use of pharmacotherapies such as sirolimus and alpelisib. It is important that clinicians understand basic and translational research advances in slow-flow vascular malformations.
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